Journal List > J Korean Diabetes Assoc > v.30(6) > 1062408

Moon, Kang, Jo, Lee, Park, Lee, Hong, Yu, Kim, Ihm, Kim, Rhim, Choi, Yoo, and Park: Effects of Type 2 Diabetes Mellitus on Risk Factors of Acute Coronary Syndrome



Diabetes mellitus (DM) is equivalent as well a risk factor of cardiovascular disease. We analyzed the effects of DM on clinical risk factors of acute coronary syndrome by comparing DM group with Non-DM group.


A total of 847 (514 males and 333 females) patients with acute coronary syndrome was selected from 1664 patients who had undergone coronary angiography (CAG). These patients comprised 105 subjects with non-ST elevation myocardial infarction (MI), 313 with ST elevation MI and 429 with unstable angina. According to the presence of DM, we retrospectively reviewed the measured basic demographics, biochemical markers and coronary angiographic findings.


In the multivariated analysis, history of hypertension (P = 0.001), C-reactive protein (CRP) level (P = 0.001) and triglyceride level (P = 0.018) were independent risk factors in type 2 diabetic group. Also the frequency of multiple coronary vessel disease was higher in DM group than non-DM group on the coronary angiographic finding


Classic risk factors for acute coronary syndrome are strong predictors in patients with type 2 DM. Among these factors, the most important powerful risk factor is history of hypertension.

Figures and Tables

Table 1
Mean Values of Basic Demographic and Laboratory Findings According to Diabetes Mellitus

BMI, Body mass index; CRP, C-reactive protein; T-Cholesterol, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol.

Table 2
Smoking Distribution According to Diabetes Mellitus
Table 3
Numbers of Pathologic Lesion of Coronary Angiography in Diabetes Mellitus and Non-diabetes Mellitus
Table 4
Multivariate Analysis for Risk Factors of Diabetes Mellitus and Non-diabetes Mellitus in Acute Coronary Syndrome

CRP, C-reactive protein; T-cholesterol, Total cholesterol.


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