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Abstract
Purpose
We aimed to verify whether the formal clinical index derived from infants and toddlers have a good association with the disease severity when we confine subjects to only infants, who undergo profound changes physically and immunologically.
Methods
We retrospectively reviewed the medical records of hospitalized infants with acute bronchiolitis caused by respiratory syncytial virus between January 1, 2010 and December 31, 2011 in three hospitals. The age, respiratory rate, presentation of chest retraction, and percutaneous oxygen saturation upon admission; presentation of fever, use of oxygen therapy and inhaled corticosteroid within 24 hours after admission were investigated. We then examined the effect of clinical index on severity of acute bronchiolitis; the mean length of stay, mean duration of fever and oxygen therapy.
Results
A total of 172 infants were studied. The mean length of stay was longer in patients younger than 3 months (P=0.015), in those with fever (P=0.028) and chest retraction (P=0.014), and in those who needed oxygen supplement (P=0.000). In the patients with fever, the mean duration of fever was longer in those who needed the oxygen supplement than those who did not (P=0.046).
Figures and Tables
Fig. 1
The age (A), chest retraction (B), fever (C), and oxygen supplement (D) were associated with the length of stay. All boxplots: median; 10th, 25th, 75th, 90th percentiles.
Fig. 2
The mean length of stay was shorter than in those who did not require saturation monitoring than those who needed saturation monitoring. There was no difference between the group of more than oxygen saturation 90% and the group of less than oxygen saturation 90%. All boxplots: median; 10th, 25th, 75th, 90th percentiles. *Student t-test. †Mann-Whitney U test.
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