An Update on Gut Microbiota and Infant's Health

Zahid Manzoor; Young-Sang Koh

doi:10.4167/jbv.2016.46.4.303

Journal List > J Bacteriol Virol > v.46(4) > 1034237

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Manzoor and Koh: An Update on Gut Microbiota and Infant's Health

Research Update (Minireview)

J Bacteriol Virol 2016;46(4):303-306.

Published online: 9 February 2016

DOI: https://doi.org/10.4167/jbv.2016.46.4.303

An Update on Gut Microbiota and Infant's Health

Zahid Manzoor, Young-Sang Koh^∗

Department of Microbiology and Immunology, School of Medicine and Brain Korea 21 PLUS Program, and Institute of Medical Science, Jeju National University, Jeju, Korea

^∗Corresponding author: Young-Sang Koh. Department of Microbiology and Immunology, Jeju National University School of Medicine, 102 Jejudaehakno, Jeju 63243, Korea. Phone: +82-64-754-3851, Fax: +82-64-702-2687, e-mail: yskoh7@jejunu.ac.kr

Received 2 December 20162 December 2016 Accepted 3 December 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Childhood malnutrition is a global problem and one of the leading cause of stunted growth, and responsible for the death of millions of children every year. Although extensive efforts have been made to promote healthy growth but results are not satisfactory and infant's health remains a challenge. Previously, it was demonstrated that undernourished children have disrupted normal pattern of intestinal microbiota and led to a proposal that it might be involved in impaired postnatal growth. Recently, various research groups focused on Malawian population and proved the role of intestinal microbiota in the stunted growth of children. In addition, one group showed the role of sialylated bovine milk oligosaccharides in promoting microbiota-dependent growth in malnourished children. Moreover, it was also revealed that Clostridium symbiosum and Ruminococcus gnavus might be used as therapeutic agent for ameliorating growth abnormalities in malnourished children. The current article summarizes the recent advancement in identifying interventions regarding health promotion of malnourished children.

Keywords: Microbiota, Stunted growth, Malnutrition, Infant's health

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