Journal List > J Korean Ophthalmol Soc > v.51(6) > 1008845

Yi, Sung, Kim, Woo, and Kim: Primary Conjunctival Epithelial Cyst in the Orbit

Abstract

Purpose

To report a case of a primary conjunctival epithelial cyst in the orbit.

Case summary

A 60-year-old woman was referred for evaluation of proptosis of the left eye, which had developed about 2 years earlier. Upon initial examination, a movable mass was palpated in the medial aspect of the left orbit. Magnetic resonance imaging of the orbit showed a 2.5 cm-sized, ovoid, cystic mass located between the left eyeball and the medial wall of the orbit. Excisional biopsy of the orbital mass was performed. The orbital mass was a well-circumscribed cystic lesion, adherent to the medial rectus muscle. Histological examination revealed that the cyst was lined with multiple layers of cuboidal epithelium with goblet cells. A diagnosis of primary conjunctival cyst was made.

Conclusions

The possibility of primary conjunctival cyst should be considered in the differential diagnosis for an orbital cystic mass.

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Figure 1.
Clinical photograph showing movable mass in the inferonasal part of the left orbit (arrows).
jkos-51-885f1.tif
Figure 2.
Axial (A) and coronal (B) CT images reveal a 2.5×2.4×1.4-cm, ovoid, cystic mass in the medial aspect of the left orbit. Lateral displacement of the left globe and pressure remodeling of the medial wall in the left orbit are shown.
jkos-51-885f2.tif
Figure 3.
Axial (A) T1-weighted MR image and coronal (B) T2-weighted MR image demonstrate a well-circum-scribed cystic lesion between the eyeball and medial wall in the left orbit. Axial (C) and sagittal (D) fat-sup-pressed contrast-enhanced T1-weighted MR images show the cystic mass which is adherent to medial rectus muscle without enhancement.
jkos-51-885f3.tif
Figure 4.
Intraoperative photograph showing a thin-walled, well-circumscribed cyst.
jkos-51-885f4.tif
Figure 5.
(A) The cystic wall is lined with nonkeratinized, cuboidal, or columnar epithelium with goblet cells (H & E stain, ×100). (B) Higher magnification showed stratified cuboidal or columnar epithelial cells and goblet cells (arrows) (H & E stain, ×400).
jkos-51-885f5.tif
Figure 6.
Immunohistochemistry for smooth muscle actin (SMA) demonstrated bundles of smooth muscle cells, surrounding the cyst incompletely (immunohistochemical staining using SMA, ×100).
jkos-51-885f6.tif
Figure 7.
Postoperative photograph showing a left esotropia of 6 prism diopters (PD) in the primary position at 2 months after surgery.
jkos-51-885f7.tif
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