Abstract
Purpose
To analyze the thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with superior segmental optic hypoplasia (SSOH) using optical coherence tomography (OCT).
Methods
Ten eyes of 10 patients with SSOH and 20 eyes of 20 subjects as normal control were evaluated. The peripapillary RNFL thickness measured by Stratus OCT was compared between the two groups.
Results
The mean RNFL thickness was significantly different between SSOH patients (72.35±14.77 µ m) and normal subjects (111.61±6.62 µ m) (p<0.001). The extent to which the RNFL thickness was below 5 percentile of normal subjects on the TSNIT graph was from the 41.7±15.53 to 110.1±7.47 scan number, which corresponded mainly with the superior nasal region. Moreover, in a clock‐ hour analysis, the peripapillary RNFL thickness of the SSOH patients decreased significantly from 10 o'clock to 6 o'clock compared to normal subjects (p<0.01).
References
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Table 1.
SSOH∗ | Control | P value‡ | |
---|---|---|---|
Patients No. (eyes) | 10 (10) | 20 (20) | |
Gender (male:female) | 3:7 | 8:12 | |
Age (years) | 44.3±14.6 (17~64) | 41.8±22.4 (21~65) | 0.948 |
SE†† (diopter) | -3.35±2.60 | -3.15±2.85 | 0.920 |
Table 2.
Visual acuity | 20/20 | Ophthalmoscopic findings | |
---|---|---|---|
Family history | - | Superior entrance of CRA# | 9 |
Maternal DM | - | Superior scleral halo | 6 |
Visual field | Thinning of superior RNFL | 10 | |
MD∗ (decibel) | -4.18±2.57 | Thinning of inferior RNFL | 5 |
PSD† (decibel) | 5.51±4.31 | Previous diagnosis | |
Disc mapping | SN‡> ST§ > NΠ | Normal tension glaucoma | 6 |
Optic neuritis | 1 |