Serous adenocarcinoma arising from ovarian endometriosis after menopause

Tae-Hee Kim; Hae-Hyeog Lee; Soo-Ho Chung; Jeong-Ja Kwak; Byoung-Ick Lee; Yeon-Pyo Hong

doi:10.5468/kjog.2010.53.4.365

Journal List > Korean J Obstet Gynecol > v.53(4) > 1006405

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Kim, Lee, Chung, Kwak, Lee, and Hong: Serous adenocarcinoma arising from ovarian endometriosis after menopause

Case Report

Korean Journal of Obstetrics and Gynecology

Korean Journal of Obstetrics and Gynecology 2010; 53(4): 365-370.

Published online: 30 April 2010

DOI: https://doi.org/10.5468/kjog.2010.53.4.365

Serous adenocarcinoma arising from ovarian endometriosis after menopause

Tae-Hee Kim, M.D.¹, Hae-Hyeog Lee, M.D.¹, Soo-Ho Chung, M.D.¹, Jeong-Ja Kwak, M.D.², Byoung-Ick Lee, M.D.³, Yeon-Pyo Hong, M.D.⁴

¹Department of Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Bucheon, Korea.

²Department of Pathology, Soonchunhyang University College of Medicine, Bucheon, Korea.

³Department of Obstetrics and Gynecology, Inha University College of Medicine, Incheon, Korea.

⁴Department of Preventive Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

Corresponding author (hhl22@chol.com, hhl22@schbc.ac.kr)

Received 4 January 2010 Accepted 15 March 2010

Abstract

Endometriosis is estrogen dependent disease in reproductive age. Endometriosis is a chronic inflammatory gynecologic disease. Problems associated with endometriosis include dysmenorrhea, dyspareunia, and infertility. Postmenopausal endometriosis is rare. Also, malignant transformation in endometriosis is rare. There is no report in Korea about serous adenocarcinoma arising from endometriosis after menopause. The authors present a case of serous adenocarcinoma arising from endometriosis after menopause with brief review of the literature.

Keywords: Serous adenocarcinoma, Endometriosis, Menopause

Figures and Tables

Fig. 1

Contrast-enhanced CT images show 7 cm sized low density mass in right side aspect of uterus.

Fig. 2

Laparoscopic finding shows right side severe adhesion and loculated cystic mass in pelvis.

Fig. 3

Pathologic findings. (A) Sections show cystic space lined by endometrial glandular cell and hemorrhage (H&E stain, ×40). (B) Low power view of tumor show closely packed papillae with fibrous core (H&E stain, ×40). (C) Immunohistochemical stain of cytokeratin 7 reveal diffuse strong reactivity (×100). (D) CD 10 immunostaining reveal reactivity.

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