Journal List > J Korean Rheum Assoc > v.17(3) > 1003739

Ha, Lee, Jung, Park, Lee, and Park: A Case of Wegener's Granulomatosis Presenting with Cerebral Infarction and Intracerebral Hemorrhage

Abstract

Wegener's granulomatosis is a multisystem necrotizing vasculitis that primarily involves the upper and lower respiratory tract and kidneys but can affect almost any organ, including the central nervous system. Cerebral infarction and intracerebral hemorrhage are rare neurologic complications of Wegener's granulomatosis. We report on a 52-year-old male patient with Wegener's granulomatosis presenting with a cerebral infarction and subsequent intracerebral hemorrhage. He was successfully treated with high dose corticosteroid and cyclophosphamide.

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Fig. 1.
Magnetic resonance imaging of the brain revealed an acute infarction in the left centrum semiovale and left basal ganglia (A, B), and magnetic resonance angiography of the brain was negative (C).
jkra-17-283f1.tif
Fig. 2.
Brain computed tomography scan showed acute intracerebral hemorrhage in the right frontal lobe, extending into the ventricles.
jkra-17-283f2.tif
Fig. 3.
Paranasal sinus computed tomography showed polypoid mucosal swelling and infiltration in the entire sinonasal cavity and an irregular infiltrative lesion in the right inferomedial orbit, suggesting chronic granulomatous disease involvement (A: transverse view, B: coronal view).
jkra-17-283f3.tif
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