Kang Min Kim; Hyun Gwang Jung; Yoon Sung Cho; Jae Hoon Chang; Tae Woo Kim; Choong Won Lee

doi:10.4078/jkra.2007.14.4.369

Journal List > J Korean Rheum Assoc > v.14(4) > 1003586

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Kim, Jung, Cho, Chang, Kim, and Lee: Manifestations Like Multiple Sclerosis in a Paitent with Rheumatoid Arthritis and Sjögren's Syndrome

Original Article

J Korean Rheum Assoc 2007;14(4):369-374.

Published online: 23 December 2007

DOI: https://doi.org/10.4078/jkra.2007.14.4.369

Manifestations Like Multiple Sclerosis in a Paitent with Rheumatoid Arthritis and Sjögren's Syndrome

Kang Min Kim, Hyun Gwang Jung, Yoon Sung Cho, Jae Hoon Chang, Tae Woo Kim, Choong Won Lee

Department of Internal Medicine, Wallace Memorial Hospital, Busan, Korea

Received 10 May 200713 July 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Demyelinating syndrome can rarely occur in Sjögren's syndrome or rheumatoid arthritis. We describe a patient of Sjögren's syndrome with multiple sclerosis-like features whose rheumatoid arthritis has been managed for 3 years. The patient presented paraparesis and urinary retention, and improved with high-dose corticosteroid therapy.

Keywords: Sjögren's syndrome, Multiple sclerosis, Rheumatoid arthritis

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Fig. 1.

FLAIR (A, B) and T2-weighted (C, D) brain MRI images show high signal lesions in the periventricular white matter and left thalamus.

Fig. 2.

T2 weighted MRI image shows discontinuous high intensity signal from C5 to T9 levels of spinal cord.

Fig. 3.

Multiple joint space narrow, ankylosis, and deformities of both hands are shown in the radiograph.

Fig. 4.

Biopsy of labial salivary gland reveals focal infiltration of lymphocytes and plasma sells around the gland. Grade 4, focus score > 1 per 4 mm² (H&E stain, x400).

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