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Lee, Choi, Jeong, Kim, and Seo: An Overview and Future Perspective on Endocrine Disruptors
Review Article
Journal of Korean Endocrine Society

Journal of Korean Endocrine Society 2009; 24(1): 7-14.

Published online: 31 March 2009

DOI: https://doi.org/10.3803/jkes.2009.24.1.7

An Overview and Future Perspective on Endocrine Disruptors

Chul Woo Lee, Kyung Hee Choi, Seok Won Jeong1, Hye Lim Kim1, Young Rok Seo1

Environmental Exposure Assessment Division, National Institute of Environmental Research, Korea.

1Department of Pharmacology, Institute for Basic of Medical Science (IBMS), School of Medicine, Kyung Hee University, Korea.

Copyright © 2009 Korean Endocrine Society

Figures and Tables

Fig. 1
Mechanism of estrogen receptor-mediated transcriptional activation induced by estrogen binding to the receptor (ERE: estrogen responsive element, hsp90: heat shock protein 90, RNA Pol II: PNA polymerase II).
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Fig. 2
Structure of the major known environmental estrogens (A) DES(diethylstilbestrol), (B) 4-Nonylphenol, (C) Bisphenol A, (D) DEHP (diethylhexylphthalate).
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Fig. 3
Microarray process. Control mRNA and endocrine disruptors treated mRNA were hybridized into cDNA respectively. aRNA were hybridized using cDNA as a template. aRNA were labeled by Cy3 and Cy5. Each sample were mixed and hybridized on the array chip for 16 hours.
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Table 1
Suspected endocrine disruptors
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