Journal List > Korean Diabetes J > v.33(5) > 1002324

Kim, Lee, Kim, Kim, Na, Kim, Kim, Baek, Kang, Lee, and Song: Depression and Self-care Behavior in Patients with Diabetes Mellitus

Abstract

Background

Depression is known to be a risk factor for type 2 diabetes mellitus. Conversely, diabetes is also a risk factor for depression, and patients with diabetes have nearly twice the risk of comorbid depression as the general population. Depression in patients with diabetes may cause poor clinical outcomes through lower adherence to self-care activities such as exercise, diet control, and glucose monitoring. Furthermore, diabetic patients with depression are more likely to suffer from microvascular or macrovascular complications. We explored the prevalence of major depressive disorder in Korean diabetic patients and its impact on self-care activities and glucose control.

Methods

We surveyed depressive symptoms and self-care activities in 191 type 2 diabetic patients from the outpatient clinic of the St. Mary's hospital. Two questionnaires were used for assessment, the Harvard Department of Psychiatry/National Depression Screening Day Scale (HANDS) and the Summary of Diabetes Self-Care Activities (SDSCA).

Results

Of the 191 respondents who completed questionnaires, 39 (20.4%) patients were categorized as having major depressive disorder. Among the depressed patients, only six (15.3%) had been previously evaluated and managed for their psychiatric problems. The incidence of depression was significantly higher in female diabetic patients compared to patients without depression (74.4% vs. 45.4%, P < 0.001). Patients with depression showed significantly poorer diet control (18.5 vs. 15.9, P = 0.046) and less glucose monitoring (4.1 vs. 2.7, P = 0.047). However, there were no differences in exercise, foot care, or smoking status between the two groups. Additionally, metabolic parameters such as HbA1C and lipid profile were not significantly different between the two groups.

Conclusion

Many diabetic patients are suffering from depression and exhibit poorer self-care activities than patients without depression. Identifying and managing depressed diabetic patients may help improve their self-care activities.

Figures and Tables

Table 1
Classification of patients according to HANDS score
kdj-33-432-i001

Data are n (%). HANDS, Harvard department of psychiatry/national depression screening day scale.

Table 2
Patients characteristics
kdj-33-432-i002

Data are n (%) or means ± SD. Statistical comparisons are between patients with scores above or below the HANDS cutoff using χ2 or Student's t test; ACR, albumin-to-creatinine ratio in random urine samples; HANDS, Harvard department of psychiatry/national depression screening day scale; HDL-cholesterol, high density lipoprotein cholesterol; LDL-cholesterol, low density lipoprotein cholesterol.

Table 3
Score of self-care behaviors by HANDS cutoff score
kdj-33-432-i003

Data are means ± SD. Student's t test were used to statistical comparisons between two groups. HANDS, Harvard department of psychiatry/national depression screening day scale.

References

1. Eaton W, Armenian H, Gallo J, Pratt L, Ford E. Depression and risk for onset of type II diabetes: A prospective population-based study. Diabetes Care. 1996. 22:1097–1102.
2. Fisher L, Skaff MM, Chesla CA, Kanter RA, Mullan JT. Contributors to depression in Latino and European-American patients with type 2 diabetes. Diabetes Care. 2001. 24:1751–1757.
3. Peyrot M, Rubin RR. Levels and risks of depression and anxiety symptomatology among diabetic adults. Diabetes Care. 1997. 20:585–590.
4. Rush WA, Whitebird RR, Rush MR, Solberg LI, O'Connor PJ. Depression in Patients with Diabetes: Does It impact clinical goals? J Am Board Fam Med. 2008. 21:392–397.
5. Katon W, von Korff M, Ciechanowski P, Russo J, Lin E, Simon G, Ludman E, Walker E, Bush T, Young B. Behavioral and clinical factors associated with depression among individuals with diabetes. Diabetes Care. 2004. 27:914–920.
6. Clouse RE, Lustman PJ, Freedland KE, Griffith LS, McGill JB, Carney RM. Depression and coronary heart disease in women with diabetes. Psychosom Med. 2003. 65:376–383.
7. Rugulies R. Depression as a predictor for coronary heart disease. a review and meta-analysis. Am J Prev Med. 2002. 23:51–61.
8. de Groot M, Anderson R, Freedland KE, Clouse RE, Lustman PJ. Association of depression and diabetes complications: a meta-analysis. Psychosom Med. 2001. 63:619–630.
9. Kessler RC, Berglund P, Demler O. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA. 2003. 289:3095–3105.
10. Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care. 2001. 24:1069–1078.
11. Noh JH, Park JK, Lee HJ, Kwon SK, Lee SH, Park JH, Ko KS, Rhee BD, Lim KH, Kim DJ. Depressive symptoms of type 2 diabetics treated with insulin compared to diabetics taking oral anti-diabetic drugs: a Korean study. Diabetes Res Clin Pract. 2005. 69:243–282.
12. Katon WJ, Rutter C, Simon G, Lin EH, Ludman E, Ciechanowski P. The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care. 2005. 28:2668–2672.
13. Egede LG, Zheng D, Simpson K. Comorbid depression is associated with increased health care use and expenditures in individuals with diabetes. Diabetes Care. 2002. 25:464–470.
14. Baer L, Jacobs DG, Meszler-Reizes J, Blais M. Development of a brief screening instrument: the HANDS. Psychother Psychosom. 2000. 69:35–41.
15. Toobert DJ, Glasgow RE. Assessing diabetes self-management: the summary of diabetes self-care activities questionnaire. Handbook of Psychology and Diabetes. 1994. Harwood Academic;351–375.
16. Toobert DJ, Hampson SE, Glasgow RE. The Summary of Diabetes Self-Care Activities Measure Results from 7 studies and a revised scale Diabete. Care. 2000. 23:943–950.
17. Eigenmann CA, Colagiuri R, Skinner TC, Trevena L. Are current psychometric tools suitable for measuring outcomes of diabetes education? Diabet Med. 2009. 26:425–436.
18. Musselman DL, Betan E, Larsen H, Phillips LS. The relationship of depression to diabetes-Type 1 and Type 2: Epidemiology, biology, and treatment. Biol Psychiatry. 2003. 54:317–329.
19. Yoo HJ. Pharmachotherapy for depressive disorder in patients with diabetes mellitus. Korean Diabetes J. 2008. 301–308.
20. Milano AF, Singer RB. Mortality in co-morbidity (II)-excess death rates derived from a follow-up study on 10025 subjects divided into groups with or without depression and diabetes mellitus. J Insur Med. 2007. 39:160–166.
21. Zhang X, Norris SL, Gregg EW, Cheng YJ, Beckles G, Kahn HS. Depressive symptoms and mortality among persons with and without diabetes. Am J Epidemiol. 2005. 161:652–660.
22. Jeffrey S, Steven A, Enrico C. Depression, Self-Care, and Medication Adherence in Type 2 Diabetes: Relationships across the full range of symptom Severity. Diabetes Care. 2007. 30:2222–2227.
23. Ciechanowski PS, Katon WJ, Russo JE. Impact of depressive symptoms on adherence, function, and costs. Arch Intern Med. 2000. 160:3278–3285.
24. Ciechanowski PS, Katon WJ, Russo JE, Hirsch IB. The relationship of depressive symptoms to symptom reporting, selfcare and glucose control in diabetes. Gen Hosp Psychiatry. 2003. 25:246–252.
25. Lin EH, Katon W, Von Korff M, Rutter C. Relationship of depression and diabetes self-care, medication adherence, and preventative care. Diabetes Care. 2004. 27:2154–2160.
26. Park HS, Hong YS, Lee HJ, Ha EH, Sung YA. Individuals with type 2 diabetes and depressive symptoms exhibited lower adherence with self-care. J Clin Epidemiol. 2004. 57:978–984.
27. Kalsekar ID, Madhaven SS, Amonkar MM, Makela EH, Elswick BL. Depression in patients with type 2 diabetes: impact on adherence to oral hypoglycemic agents. Ann Pharmacother. 2006. 40:605–611.
28. Kilbourne AM, Reynolds CF, Good CB, Sereika SM, Justice AC, Fine MJ. How does depression influence diabetes medication adherence in older patients? Am J Geriatr Psychiatry. 2005. 13:202–210.
29. Lustman P, Anderson R, Freedland K. Depression and Poor Glycemic Control A meta-analytic review of the literature. Diabetes Care. 2000. 23:934–942.
30. Winkley K, Ismail K, Landau S, Eisler I. Psychological interventions to improve glycaemic control in patients with type 1 diabetes: systematic review and meta-analysis of randomised controlled trials. BMJ. 2006. 333:65.
31. Halford K, Goodall TA, Nicholson JM. Diet and diabetes (II): A controlled trial of problem solving to improve dietary selfmanagement in patients with insulin-depenedent diabetes. Psychology and Health. 1997. 12:231–238.
32. Stenström U, Göth A, Carlsson C, Andersson PO. Stress management training as related to glycemic control and mood in adults with Type 1 diabetes mellitus. Diabetes Res Clin Pract. 2003. 60:147–152.
33. van der Ven NC, Hogenelst MH, Tromp-Wever AM. Short-term effects of cognitive behavioural group training (CBGT) in adult type 1 diabetes patients in prolonged poor glycaemic control. Diabet Med. 2005. 22:1619–1623.
34. Okamura F, Tashiro A, Utumi A. Insulin resistance in patients with depression and its changes during the clinical course of depression: minimal model analysis. Metab Clin Exp. 2000. 49:1255–1260.
TOOLS
Similar articles