J Korean Ophthalmol Soc JKOS Journal of the Korean Ophthalmological Society 0378-6471 2092-9374 The Korean Ophthalmological Society 10.3341/jkos.2020.61.3.307 Case Report Regression of Neovascularization after Using Only Intraocular Pressure-lowering Medications in Neovascular Glaucoma Lee Sang Wook MD Kim Ko Eun MD PhD Department of Ophthalmology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea. Address reprint requests to Ko Eun Kim, MD, PhD. Department of Ophthalmology, Nowon Eulji Medical Center, Eulji University School of Medicine, #68 Hangeulbiseok-ro, Nowon-gu, Seoul 01830, Korea. Tel: 82-2-970-8271, Fax: 82-2-970-8862, csckek@gmail.com 03 2020 17 03 2020 61 3 307 312 20 06 2019 25 08 2019 21 02 2020 ©2020 The Korean Ophthalmological Society 2020 The Korean Ophthalmological Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose

To report a case of neovascular glaucoma after intraocular lens iris fixation, in which the neovascularization of the iris and the anterior chamber improved with only intraocular pressure (IOP) lowering agents, without treatment of the underlying cause.

 Case summary

A 74-year-old woman who had undergone bilateral cataract surgery presented with left ocular pain and headache that started 3 days previously. At the initial examination, the best-corrected visual acuity was 0.9, and the IOP was 38 mmHg in the left eye. Slit-lamp examination of the left eye revealed diffuse iris neovascularization and several polypropylene suture knots fixated in the superior and inferior iris. Gonioscopic examination revealed angle neovascularization in all quadrants, with focal peripheral anterior synechia in the inferior quadrant. Fundus examination presented inferior neuroretinal rim thinning and an inferior retinal nerve fiber layer defect in the left eye. Fluorescent angiography showed no ischemic retinal lesions, with the exception of several retinal microaneurysms. Six months after topical IOP-lowering treatment in the left eye, the IOP was 10 mmHg, and neovascularization of the iris and angle had regressed completely.

 Conclusions

In the case of early-stage neovascular glaucoma with partial angle closure not associated with retinal ischemia, IOP-lowering treatment can be effective without other invasive procedures.

 Angle neovascularization Intraocular lens fixation Intraocular pressure-lowering medication Iris neovascularization Neovascular glaucoma

The authors have no conflicts to disclose.

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