Korean J Occup Environ Med KJOEM Korean Journal of Occupational and Environmental Medicine 1225-3618 The Korean Society of Occupational and Environmental Medicine 10.35371/kjoem.2009.21.3.289 Case Report A Case of Cerebellar Dysfunction After Acute Organotin Poisoning Kim Suk Hwan Yoo Cheol In Kwon Jee Hyun Bae Jin Ho Weon Young Cheol Kim Yangho Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. Department of Neurology and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. yanghokm@nuri.net 09 2009 29 01 2019 21 3 289 292 Copyright © 2012 The Korean Society of Occupational and Environmental Medicine 2009 BACKGROUND

We performed a follow-up study of an acute organotin poisoning case on the neurological sequelae that remained after 3 years since diagnosis.

 CASE

In the previous study, a 43-year-old male was reported for acute organotin poisoning. After 3 years, the neurological sequelae were studied using neurological examination, cognitive tests, neurobehavioral tests (by CAYSYS 2000(TM)), brain magnetic resonance imaging (MRI), and 18F-fluorodeoxyglucose (18F-FDG) PET/CT. Upon neurological examination and other tests, orientation was improved compared to that 3 years before, but cerebellar ataxia, dysmetria and dysdiadochokinesia remained the same, with little change. Brain MRI showed cerebellar atrophy. 18F-FDG PET/CT revealed mildly decreased metabolic activity in the pons and in both cerebellar hemispheres.

 DISCUSSION

This is the first brain MRI study on cerebellar atrophy caused by organotin poisoning. Cerebellar ataxia was confirmed by decreased metabolic activity in 18F-FDG PET/CT.

 Organotin Cerebellar ataxia Fluorodeoxyglucose F18