<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.0" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">pmp</journal-id>
<journal-title-group>
<journal-title>Progress in Medical Physics</journal-title>
<abbrev-journal-title>Progress in Medical Physics</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">2508-4445</issn>
<issn pub-type="epub">2508-4453</issn>
<publisher>
<publisher-name>Korean Society of Medical Physics</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.14316/pmp.2017.28.3.129</article-id>
<article-id pub-id-type="publisher-id">pmp-28-129</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>A Pilot Study of the Scanning Beam Quality Assurance Using Machine Log Files in Proton Beam Therapy</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en">
<surname>Chung</surname><given-names>Kwangzoo</given-names></name>
<xref ref-type="aff" rid="aff1-pmp-28-129"/>
<xref ref-type="corresp" rid="c1-pmp-28-129"/>
</contrib>
<aff id="aff1-pmp-28-129" xml:lang="en">Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, <country>Korea</country></aff>
</contrib-group>
<author-notes>
<corresp id="c1-pmp-28-129"><bold>Corresponding author</bold> Kwangzoo Chung (<email>kchung@skku.edu</email>) Tel: 82-2-3410-1353 Fax: 82-2-3410-2619</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>9</month><year>2017</year></pub-date>
<pub-date pub-type="epub"><day>17</day><month>9</month><year>2017</year></pub-date>
<volume>28</volume><issue>3</issue>
<fpage>129</fpage><lpage>133</lpage>
<history>
<date date-type="received"><day>25</day><month>09</month><year>2017</year></date>
<date date-type="Revised"><day>29</day><month>09</month><year>2017</year></date>
<date date-type="accepted"><day>30</day><month>09</month><year>2017</year></date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2017 Korean Society of Medical Physics</copyright-statement>
<copyright-year>2017</copyright-year>
<license><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license>
</permissions>
<abstract xml:lang="en">
<title>Abstract</title>
<p>The machine log files recorded by a scanning control unit in proton beam therapy system have been studied to be used as a quality assurance method of scanning beam deliveries. The accuracy of the data in the log files have been evaluated with a standard calibration beam scan pattern. The proton beam scan pattern has been delivered on a gafchromic film located at the isocenter plane of the proton beam treatment nozzle and found to agree within &#x00B1;1.0 mm. The machine data accumulated for the scanning beam proton therapy of five different cases have been analyzed using a statistical method to estimate any systematic error in the data. The high-precision scanning beam log files in line scanning proton therapy system have been validated to be used for off-line scanning beam monitoring and thus as a patient-specific quality assurance method. The use of the machine log files for patient-specific quality assurance would simplify the quality assurance procedure with accurate scanning beam data.</p>
</abstract>
<kwd-group xml:lang="en">
<kwd>Proton beam therapy</kwd>
<kwd>Scanning beam</kwd>
<kwd>Quality assurance</kwd>
<kwd>Machine log file</kwd>
</kwd-group>
</article-meta>
</front>
<back>
<ref-list xml:lang="en">
<title>REFERENCES</title>
<ref id="b1"><label>1.</label><element-citation publication-type="journal"><collab>RR Wilson</collab> <article-title>Radiological use of fast protons</article-title> <source>Radiology.</source> <year>1946</year><volume>47</volume> <fpage>487</fpage><lpage>91</lpage></element-citation></ref>
<ref id="b2"><label>2.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kang</surname> <given-names>JK</given-names></name> <name><surname>MS Kim</surname> <given-names>WI</given-names></name></person-group> <article-title>Jang, et. al. The clinical utilization of radiation therapy in Korea between 2009 and 2013</article-title> <source>Radiat Oncol J.</source> <year>2016</year><volume>34</volume> <fpage>88</fpage><lpage>95</lpage></element-citation></ref>
<ref id="b3"><label>3.</label><element-citation publication-type="journal"><collab>M Jermann</collab> <article-title>Particle therapy statistics in 2014</article-title> <source>Int J Particle Ther.</source> <year>2015</year><volume>2</volume> <fpage>50</fpage><lpage>4</lpage></element-citation></ref>
<ref id="b4"><label>4.</label><element-citation publication-type="journal"><collab>H Li, N Sahoo, F Poenisch et</collab> <article-title>al. Use of treatment log files in spot scanning proton therapy as part of patient-specific quality assurance</article-title> <source>Med Phys.</source> <year>2013</year><volume>40</volume> <fpage>021703</fpage><lpage>1</lpage><comment>-11.</comment></element-citation></ref>
<ref id="b5"><label>5.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Scandurra</surname> <given-names>D</given-names></name> <name><surname>Albertini</surname> <given-names>F</given-names></name> <name><surname>Meer</surname> <given-names>R</given-names></name> <etal/></person-group> <article-title>Assessing the quality of proton PBS treatment delivery using machine log files: comprehensive analysis of clinical treatments delivered at PSI Gantry 2</article-title> <source>Phys Med Biol.</source> <year>2016</year><volume>61</volume> <fpage>1171</fpage><lpage>81</lpage></element-citation></ref>
<ref id="b6"><label>6.</label><element-citation publication-type="journal"><collab>K Chung, Y Han, J Kim et</collab> <article-title>al. The first private-hospital based proton therapy center in Korea: Status of the Proton Therapy Center at Samsung Medical Center</article-title> <source>Radiat Oncol J.</source> <year>2015</year><volume>33</volume> <fpage>337</fpage><lpage>43</lpage></element-citation></ref>
<ref id="b7"><label>7.</label><element-citation publication-type="journal"><collab>K Chung, J Kim, DH Kim, S Ahn, Y Han</collab> <article-title>The proton therapy nozzles at Samsung Medical Center: A Monte Carlo simulation study using TOPAS</article-title> <source>J Korean Phys Soc.</source> <year>2015</year><volume>67</volume> <fpage>170</fpage><lpage>4</lpage></element-citation></ref>
<ref id="b8"><label>8.</label><element-citation publication-type="journal"><collab>K Chung, Y Han, SH Ahn, JS Kim, H Nonaka</collab> <article-title>Commissioning and Validation of a Dedicated Scanning Nozzle at Samsung Proton Therapy Center</article-title> <source>Prog Med Phys.</source> <year>2016</year><volume>27</volume> <fpage>267</fpage><lpage>71</lpage></element-citation></ref>
<ref id="b9"><label>9.</label><element-citation publication-type="other"><source>GAFChromic<sup>TM</sup> EBT3 film specifications</source> <comment>Available at</comment> <ext-link ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://www.gafchromic.com">www.gafchromic.com</ext-link></element-citation></ref>
<ref id="b10"><label>10.</label><element-citation publication-type="journal"><collab>G Moliere</collab> <article-title>Theorie der Streuung schneller geladener Teilchen II. Mehrfach-und Vielfachstreuung</article-title> <source>Z Naturforsch A: Phys Sci.</source> <year>1948</year><volume>3a</volume> <fpage>78</fpage><lpage>97</lpage></element-citation></ref>
</ref-list>
<sec sec-type="display-objects">
<title>Figures and Tables</title>
<fig id="F1-pmp-28-129" position="float">
<label>Fig. 1.</label>
<caption xml:lang="en"><p>A scanned EBT3 film irradiated with the standard scan pattern composed of 5x5 points (230 MeV).</p></caption>
<graphic xlink:href="pmp-28-129f1.tif"/>
</fig>
<fig id="F2-pmp-28-129" position="float">
<label>Fig. 2.</label>
<caption xml:lang="en"><p>An example of scanning beam information recorded in the scanning control unit (Top left: x-position in time, top right: y-position in time, bottom left: monitor count in time, bottom right: x-position vs. y-position. Raw data without pedestal/noise reduction).</p></caption>
<graphic xlink:href="pmp-28-129f2.tif"/>
</fig>
<fig id="F3-pmp-28-129" position="float">
<label>Fig. 3.</label>
<caption xml:lang="en"><p>A scanning beam information recorded in the scanning control unit (one sample layer of a patient beam delivery plan).</p></caption>
<graphic xlink:href="pmp-28-129f3.tif"/>
</fig>
<table-wrap id="T1-pmp-28-129" position="float">
<label>Table 1.</label>
<caption xml:lang="en"><p>The summary of pre-treatment QA log file analysis. The &#x201C;ds&#x201D; stands for the displacement of the recorded position from the planned position. For a given field (case), the entire energy layers (number of layers) have been analyzed.</p></caption>
<table frame="hsides" rules="all">
<thead>
<tr>
<th valign="middle" align="center" rowspan="2">Cases</th>
<th valign="middle" align="center" rowspan="2">Number of layers</th>
<th valign="middle" align="center">Average of ds</th>
<th valign="middle" align="center">Standard deviation</th>
</tr>
<tr>
<th valign="middle" align="left">[mm]</th>
<th valign="middle" align="center">of ds [mm]</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">Case 1</td>
<td valign="middle" align="center">15</td>
<td valign="middle" align="center">0.09</td>
<td valign="middle" align="center">0.09</td>
</tr>
<tr>
<td valign="middle" align="left">Case 2</td>
<td valign="middle" align="center">17</td>
<td valign="middle" align="center">0.11</td>
<td valign="middle" align="center">0.10</td>
</tr>
<tr>
<td valign="middle" align="left">Case 3</td>
<td valign="middle" align="center">23</td>
<td valign="middle" align="center">0.15</td>
<td valign="middle" align="center">0.07</td>
</tr>
<tr>
<td valign="middle" align="left">Case 4</td>
<td valign="middle" align="center">18</td>
<td valign="middle" align="center">0.10</td>
<td valign="middle" align="center">0.11</td>
</tr>
<tr>
<td valign="middle" align="left">Case 5</td>
<td valign="middle" align="center">11</td>
<td valign="middle" align="center">0.06</td>
<td valign="middle" align="center">0.14</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
</back>
</article>