<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.0" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">jkss</journal-id>
<journal-title-group>
<journal-title>Journal of Korean Society of Spine Surgery</journal-title>
<abbrev-journal-title>Journal of Korean Spine Surg</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">2093-4378</issn>
<issn pub-type="epub">2093-4386</issn>
<publisher>
<publisher-name>Korean Society of Spine Surgery</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.4184/jkss.2011.18.2.64</article-id>
<article-id pub-id-type="publisher-id">jkss-18-64</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Clinical Results of Unilateral Partial Vertebroplasty(UPVP) in Osteoporotic Vertebral Fracture</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en">
<surname>Yang</surname> <given-names>Jun-Young</given-names></name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="aff1-jkss-18-64"/>
<xref ref-type="corresp" rid="c1-jkss-18-64"/>
</contrib>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en">
<surname>Lee</surname> <given-names>June-Kyu</given-names></name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="aff1-jkss-18-64"/>
</contrib>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en">
<surname>Cha</surname> <given-names>Soo-Min</given-names></name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="aff1-jkss-18-64"/>
</contrib>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en">
<surname>Joo</surname> <given-names>Yong-Bum</given-names></name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="aff1-jkss-18-64"/>
</contrib>
<aff id="aff1-jkss-18-64" xml:lang="en">Department of Orthopaedic Surgery, Research Institute of Medical Science, Chungnam National University School of Medicine, Daejeon, <country>Korea</country></aff>
</contrib-group>
<author-notes>
<corresp id="c1-jkss-18-64">Corresponding author: Jun-Young Yang, M.D. Department of Orthopedic Surgery, Chungnam National University School of Medicine, 640, Daesa-Dong, Jung-Gu, Daejeon, Korea TEL: 82-42-280-7351, FAX: 82-42-252-7098 E-mail: <email>jyyang@cnu.ac.kr</email></corresp>
</author-notes>
<pub-date pub-type="ppub"><month>3</month><year>2011</year></pub-date>
<pub-date pub-type="epub"><day>21</day><month>3</month><year>2011</year></pub-date>
<volume>18</volume><issue>2</issue>
<fpage>64</fpage><lpage>69</lpage>
<history>
<date date-type="received"><day>03</day><month>08</month><year>2010</year></date>
<date date-type="rev-recd"><day>31</day><month>03</month><year>2011</year></date>
<date date-type="accepted"><day>07</day><month>04</month><year>2011</year></date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2011 Korean Society of Spine Surgery</copyright-statement>
<copyright-year>2011</copyright-year>
<license><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license>
</permissions>
<abstract xml:lang="en">
<title>Abstract</title>
<sec>
<title>Study Design</title>
<p>This is a prospective clinical study</p>
</sec>
<sec>
<title>Objectives</title>
<p>We wanted to compare the clinical results of conventional vertebroplasty(VP) and the newly devised unilateral partial vertebroplasty(UPVP)\.</p>
</sec>
<sec>
<title>Summary of Literature Review</title>
<p>There has not been any study on how to reduce the amount of cement used while maintaining the height of the vertebral body and minimizing the adjacent compression fractures.</p>
</sec>
<sec>
<title>Materials and Methods</title>
<p>From 2004 to 2008, Group 1 underwent VP and group 2 underwent UPVP. We compared the difference of the VAS score, the period of hospitalization, the infused amount of cement, the progression of the vertebral body collapse and fresh fracture of the adjacent vertebral body on the followup simple radiographs.</p>
</sec>
<sec>
<title>Results</title>
<p>In group 1, the mean VAS score changed from 6.69 to 2.80, the mean period of hospitalization was 2.30 days and the mean amount of cement infused was 6.50cc. The degree of vertebral body collapse was 0.83, 0.76, 0.69 and 0.63 on followup, and 3 cases had fresh fracture. In group 2, the mean VAS score changed from 6.41 to 2.61, the mean period of hospitalization was 2.23 days and the mean amount of cement infused was 3.74cc. The degree of collapse was 0.71, 0.69, 0.68 and 0.63 on follow up and 1 case had fresh fracture. The two groups showed no statistical significance for the change of the VAS score and the period of hospitalization, and the amount of cement was significantly less in group 2. The degree of collapse was not significantly different on the 4 times of followup. The frequency of fresh fracture was significantly less in group 2.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>UPVP could achieve similar results for pain relief, the period of hospitalization and vertebral body collapse as compared to that of VP, but fresh fracture of the adjacent vertebral body was less. So, UPVP could be a better method than VP.</p>
</sec>
</abstract>
<kwd-group xml:lang="en">
<kwd>Unilateral pedicle</kwd>
<kwd>Osteoporotic Compression Fracture</kwd>
<kwd>Vertebroplasty</kwd>
<kwd>Unilateral Partial Vertebroplasty</kwd>
</kwd-group>
</article-meta>
</front>
<back>
<ref-list xml:lang="en">
<title>REFERENCES</title>
<ref id="b1"><label>1.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cho</surname> <given-names>YS</given-names></name> <name><surname>Cho</surname> <given-names>SD</given-names></name> <name><surname>Kim</surname> <given-names>BS</given-names></name> <name><surname>Park</surname> <given-names>TW</given-names></name> <name><surname>Lew</surname> <given-names>S</given-names></name> <name><surname>Hwang</surname> <given-names>SY</given-names></name></person-group> <article-title>Kummell&#x0027;s disease managed by percutaneous vertebroplasty</article-title> <source>J Korean Soc Spine Surg</source> <year>2001</year> <volume>8</volume> <fpage>226</fpage><lpage>34</lpage></element-citation></ref>
<ref id="b2"><label>2.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lyles</surname> <given-names>KW</given-names></name> <name><surname>Gold</surname> <given-names>DT</given-names></name> <name><surname>Shipp</surname> <given-names>KM</given-names></name> <name><surname>Pieper</surname> <given-names>CF</given-names></name> <name><surname>Martinez</surname> <given-names>S</given-names></name> <name><surname>Mulhausen</surname> <given-names>PL</given-names></name></person-group> <article-title>Association of Osteoporotic Vertebral Compression Fractures with Impaired Functional Status</article-title> <source>Am J Med</source> <year>1993</year> <volume>94</volume> <fpage>595</fpage><lpage>601</lpage></element-citation></ref>
<ref id="b3"><label>3.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cooper</surname> <given-names>C</given-names></name> <name><surname>Melton</surname> <given-names>L</given-names> <suffix>3rd</suffix></name></person-group> <article-title>Vertebral Fractures</article-title> <source>BMJ</source> <year>1992</year> <volume>304</volume> <fpage>1634</fpage><lpage>5</lpage></element-citation></ref>
<ref id="b4"><label>4.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hasegawa</surname> <given-names>K</given-names></name> <name><surname>Abe</surname> <given-names>M</given-names></name> <name><surname>Washio</surname> <given-names>T</given-names></name> <name><surname>Hara</surname> <given-names>T</given-names></name></person-group> <article-title>An Experimental Study on the Interface Strength between Titanium Mesh Cage and Vertebra in Reference to Vertebral Bone Mineral Density</article-title> <source>Spine (Phila Pa 1976)</source> <year>2001</year> <volume>26</volume> <fpage>957</fpage><lpage>63</lpage></element-citation></ref>
<ref id="b5"><label>5.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lotz</surname> <given-names>JC</given-names></name> <name><surname>Hu</surname> <given-names>SS</given-names></name> <name><surname>Chiu</surname> <given-names>DF</given-names></name> <name><surname>Yu</surname> <given-names>M</given-names></name> <name><surname>Colliou</surname> <given-names>O</given-names></name> <name><surname>Poser</surname> <given-names>RD</given-names></name></person-group> <article-title>Carbonated Apatite Cement Augmentation of Pedicle Screw Fixation in the Lumbar Spine</article-title> <source>Spine (Phila Pa 1976)</source> <year>1997</year> <volume>22</volume> <fpage>2716</fpage><lpage>23</lpage></element-citation></ref>
<ref id="b6"><label>6.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Moore</surname> <given-names>D</given-names></name> <name><surname>Maitra</surname> <given-names>R</given-names></name> <name><surname>Farjo</surname> <given-names>L</given-names></name> <name><surname>Graziano</surname> <given-names>G</given-names></name> <name><surname>Goldstein</surname> <given-names>S</given-names></name></person-group> <article-title>Restoration of Pedicle Screw Fixation with an in situ setting Calcium Phosphate Cement</article-title> <source>Spine (Phila Pa 1976)</source> <year>1997</year> <volume>22</volume> <fpage>1696</fpage><lpage>705</lpage></element-citation></ref>
<ref id="b7"><label>7.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ryu</surname> <given-names>KS</given-names></name> <name><surname>Park</surname> <given-names>CK</given-names></name></person-group> <article-title>A Management for Osteoporotic Bursting Fractures of the Thoracic and Lumbar Spines in the Aged: Posterior Approach with Intraoperative Vertebroplasty</article-title> <source>J Korean Neurosurg Soc</source> <year>2003</year> <volume>33</volume> <fpage>259</fpage><lpage>63</lpage></element-citation></ref>
<ref id="b8"><label>8.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>CH</given-names></name> <name><surname>Choi</surname> <given-names>YJ</given-names></name> <name><surname>Hwang</surname> <given-names>JK</given-names></name> <name><surname>Kim</surname> <given-names>KH</given-names></name> <name><surname>Lee</surname> <given-names>JH</given-names></name> <name><surname>Song</surname> <given-names>JS</given-names></name></person-group> <article-title>Long term outcome of Vertebroplasty in the Treatment of Osteoporotic Compression Fracture</article-title> <source>J Korean Soc Spine Surg</source> <year>2005</year> <volume>12</volume> <fpage>69</fpage><lpage>74</lpage></element-citation></ref>
<ref id="b9"><label>9.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Deramond</surname> <given-names>H</given-names></name> <name><surname>Depriester</surname> <given-names>C</given-names></name> <name><surname>Galibert</surname> <given-names>P</given-names></name> <name><surname>Le Gars</surname> <given-names>D</given-names></name></person-group> <article-title>Percutaneous Vertebroplasty with Polymethylmethacrylate. Technique, indications, and results</article-title> <source>Radiol Clin North Am</source> <year>1998</year> <volume>36</volume> <fpage>533</fpage><lpage>46</lpage></element-citation></ref>
<ref id="b10"><label>10.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Liebschner</surname> <given-names>MA</given-names></name> <name><surname>Rosenberg</surname> <given-names>WS</given-names></name> <name><surname>Keaveny</surname> <given-names>TM</given-names></name></person-group> <article-title>Effects of Bone Cement Volume and Distribution on Vertebral Stiffness after Vertebroplasty</article-title> <source>Spine (Phila Pa 1976)</source> <year>2001</year> <volume>26</volume> <fpage>1547</fpage><lpage>54</lpage></element-citation></ref>
<ref id="b11"><label>11.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Belkoff</surname> <given-names>S</given-names></name> <name><surname>Deramond</surname> <given-names>H</given-names></name> <name><surname>Mathis</surname> <given-names>J</given-names></name> <name><surname>Jasper</surname> <given-names>L</given-names></name></person-group> <article-title>Vertebroplasty: The Biomechanical Effect of Cement Volume</article-title> <source>Trans Orthop Res Soc</source> <year>2000</year> <volume>46</volume> <fpage>356</fpage></element-citation></ref>
<ref id="b12"><label>12.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Song</surname> <given-names>JC</given-names></name> <name><surname>Bak</surname> <given-names>KH</given-names></name> <name><surname>Cho</surname> <given-names>DC</given-names></name></person-group> <article-title>Hong HJ, Kim JM, Kim CH. The Effect of Early Percutaneous Vertebroplasty in Occult Osteoporotic Vertebral Fracture</article-title> <source>Korean J spine</source> <year>2008</year> <volume>5</volume> <fpage>173</fpage><lpage>7</lpage></element-citation></ref>
<ref id="b13"><label>13.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fleiss</surname> <given-names>JL</given-names></name> <name><surname>Coheni</surname> <given-names>J</given-names></name></person-group> <article-title>The Equivalence of Weighted Kappa and the Intraclass Correlation Coefficient as Measures of Reliability</article-title> <source>Educ Psychol Meas</source> <year>1973</year> <volume>33</volume> <fpage>613</fpage><lpage>9</lpage></element-citation></ref>
<ref id="b14"><label>14.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kim</surname> <given-names>BJ</given-names></name> <name><surname>Kim</surname> <given-names>JH</given-names></name> <name><surname>Seo</surname> <given-names>JG</given-names></name> <name><surname>Kim</surname> <given-names>YC</given-names></name></person-group> <article-title>Comparison of the Results of Percutaneous Vertebroplasty for Treating Osteoporotic Vertebral Compression Fracture and Posttraumatic Vertebral Collapse (Kummell&#x0027;s disease)</article-title> <source>J Korean Soc Spine Surg</source> <year>2005</year> <volume>12</volume> <fpage>349</fpage><lpage>57</lpage></element-citation></ref>
<ref id="b15"><label>15.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chen</surname> <given-names>LH</given-names></name> <name><surname>Lai</surname> <given-names>PL</given-names></name> <name><surname>Chen</surname> <given-names>WJ</given-names></name></person-group> <article-title>Unipedicle Percutaneous Vertebroplasty for Spinal Intraosseous Vacuum Cleft</article-title> <source>Clin Orthop Relat Res</source> <year>2005</year> <volume>435</volume> <fpage>148</fpage><lpage>53</lpage></element-citation></ref>
<ref id="b16"><label>16.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Galibert</surname> <given-names>P</given-names></name> <name><surname>Deramond</surname> <given-names>H</given-names></name> <name><surname>Rosat</surname> <given-names>P</given-names></name> <name><surname>Le Gars</surname> <given-names>D</given-names></name></person-group> <article-title>Preliminary Note on the Treatment of Vertebral Angioma by Percutaneous Acrylic Vertebroplasty</article-title> <source>Neurochirurgie</source> <year>1987</year> <volume>33</volume> <fpage>166</fpage><lpage>8</lpage></element-citation></ref>
<ref id="b17"><label>17.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sj&#x00F6; str&#x00F6; m</surname> <given-names>L</given-names></name> <name><surname>Karlstr&#x00F6; m</surname> <given-names>G</given-names></name> <name><surname>Pech</surname> <given-names>P</given-names></name> <name><surname>Rauschning</surname> <given-names>W</given-names></name></person-group> <article-title>Indirect Spinal Canal Decompression in Burst Fractures Treated with Pedicle Screw Instrumentation</article-title> <source>Spine (Phila Pa 1976)</source> <year>1996</year> <volume>21</volume> <fpage>113</fpage><lpage>23</lpage></element-citation></ref>
<ref id="b18"><label>18.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Genant</surname> <given-names>HK</given-names></name> <name><surname>Wu</surname> <given-names>CY</given-names></name> <name><surname>van Kuijk</surname> <given-names>C</given-names></name> <name><surname>Nevitt</surname> <given-names>MC</given-names></name></person-group> <article-title>Vertebral Fracture Assessment using a Semiquantitative Technique</article-title> <source>J Bone Miner Res</source> <year>1993</year> <volume>8</volume> <fpage>1137</fpage><lpage>48</lpage></element-citation></ref>
<ref id="b19"><label>19.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Heini</surname> <given-names>PF</given-names></name> <name><surname>Berlemann</surname> <given-names>U</given-names></name> <name><surname>Kaufmann</surname> <given-names>M</given-names></name> <name><surname>Lippuner</surname> <given-names>K</given-names></name> <name><surname>Fankhauser</surname> <given-names>C</given-names></name> <name><surname>van Landuyt</surname> <given-names>P</given-names></name></person-group> <article-title>Augmentation of Mechanical Properties in Osteoporotic Vertebral Bones&#x2013;a Biomechanical Investigation of Vertebroplasty Efficacy with Different Bone Cements</article-title> <source>Eur Spine J</source> <year>2001</year> <volume>10</volume> <fpage>164</fpage><lpage>71</lpage></element-citation></ref>
<ref id="b20"><label>20.</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>White</surname> <given-names>AA</given-names></name> <name><surname>Panjabi</surname> <given-names>MM</given-names></name></person-group> <source>Clinical Biomechanics of the Spine</source> <edition>2nd ed.</edition> <publisher-loc>Philadelphia</publisher-loc> <publisher-name>Lippincott</publisher-name> <year>1990</year></element-citation></ref>
<ref id="b21"><label>21.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Belkoff</surname> <given-names>SM</given-names></name> <name><surname>Maroney</surname> <given-names>M</given-names></name> <name><surname>Fenton</surname> <given-names>DC</given-names></name> <name><surname>Mathis</surname> <given-names>JM</given-names></name></person-group> <article-title>An in vitro Biomechanical Evaluation of Bone used in Percutaneous Vertebroplasty</article-title> <source>Bone</source> <year>1999</year> <volume>25</volume> <fpage>23</fpage><lpage>6</lpage></element-citation></ref>
<ref id="b22"><label>22.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kayanja</surname> <given-names>MM</given-names></name> <name><surname>Togawa</surname> <given-names>D</given-names></name> <name><surname>Lieberman</surname> <given-names>IH</given-names></name></person-group> <article-title>Biomechanical Changes after the Augmentation of Experimental Osteoporotic Vertebral Compression Fractures in the Cadaveric Thoracic Spine</article-title> <source>Spine J</source> <year>2005</year> <volume>5</volume> <fpage>55</fpage><lpage>63</lpage></element-citation></ref>
<ref id="b23"><label>23.</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Boger</surname> <given-names>A</given-names></name> <name><surname>Heini</surname> <given-names>P</given-names></name> <name><surname>Windolf</surname> <given-names>M</given-names></name> <name><surname>Schneider</surname> <given-names>E</given-names></name></person-group> <article-title>Adjacent Vertebral Failure after Vertebroplasty: a Biomechanical Study of Low-modulus PMMA Cement</article-title> <source>Eur Spine J</source> <year>2007</year> <volume>16</volume> <fpage>2118</fpage><lpage>25</lpage></element-citation></ref>
</ref-list>
<sec sec-type="display-objects">
<title>Figures</title>
<fig id="F1-jkss-18-64" position="float">
<label>Fig. 1.</label>
<caption xml:lang="en"><p>(A)Simple AP radiographs of unilateral partial vertebroplasty(UPVP). (B) Through lateral view, we check the compression ratio during followup.</p></caption>
<graphic xlink:href="jkss-18-64f1.tif"/>
</fig>
</sec>
</back>
</article>