PURPOSE: To assess the usefulness of CISS images in the diagnosis of intraocular lesions, we compared CISSimages with 3mm and 1mm sliced spin-echo T2-weighted images. MATERIALS AND METHODS: In 14 patients with 15intraocular lesions(retinal detachment 10, choroidal melanoma, 2 ; cavernous hemangioma, 1 ; PHPV, 1 ; andretinoblastoma, 1). we used a 1.5T MR unit obtain CISS images and 3mm and 1mm sliced spin-echo T2-weighted images.All lesions were analyzed, and after dividing them into two subgroups(linear lesions, n=11 ; mass lesions, n=4),CISS and spin-echo T2-weighted images were compared for detection rate and conspicuity. RESULTS: With regard tothese two parameters, CISS images were superior to 1mm and 3mm sliced spin-echo T2-weighted images. For theassessment of linear lesions, CISS images (detection rate, 100% ; conspicuity, 2.88) were superior to both 1mm and3mm sliced spin-echo T2-weighted images. For mass lesions CISS images were superior to 3mm sliced spin-echoT2-weighted images, but for conspicuity, there was no significant difference between CISS images (2.75) and 1mmsliced spin-echo T2-weighted images(2.2). CONCLUSION: Due to their higher detection rate and greater conspicuity,CISS images were superior to spin-echo T2-weighted images for the diagnosis of intraocular lesions less than 3mmin diameter ; for the diagnosis of intraocular lesions, they might therefore be a useful adjunct to SE images.