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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">jkd</journal-id>
<journal-title-group>
<journal-title>The Journal of Korean Diabetes</journal-title>
<abbrev-journal-title>J Korean Diabetes</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">2233-7431</issn>
<issn pub-type="epub">2714-0547</issn>
<publisher>
<publisher-name>Korean Diabetes Association</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.4093/jkd.2016.17.1.41</article-id>
<article-id pub-id-type="publisher-id">jkd-17-41</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Information Desk</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Alcohol Consumption and Diabetes Mellitus</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en"><surname>Chung</surname><given-names>Hye-Kyung</given-names></name>
<xref ref-type="corresp" rid="c1-jkd-17-41"/>
<xref ref-type="aff" rid="aff1-jkd-17-41"/>
</contrib>
<aff id="aff1-jkd-17-41">Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea</aff>
</contrib-group>
<author-notes>
<corresp id="c1-jkd-17-41">Corresponding author: Hye-Kyung Chung Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea, E-mail: <email>chk@yuhs.ac</email></corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>01</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>10</day>
<month>01</month>
<year>2016</year>
</pub-date>
<volume>17</volume>
<issue>1</issue>
<fpage>41</fpage>
<lpage>45</lpage>
<history>
<date date-type="rev-recd"><day>24</day><month>01</month><year>2016</year></date>
<date date-type="accepted"><day>05</day><month>02</month><year>2016</year></date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2016 Korean Diabetes Association</copyright-statement>
<copyright-year>2016</copyright-year>
<license><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0">http://creativecommons.org/licenses/by-nc/3.0</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license>
</permissions>
<abstract xml:lang="en">
<title>Abstract</title>
<p>The effects of alcohol consumption on diabetic patients are still unclear and inconclusive. Generally, light-to-moderate alcohol consumption (&#x003C; 3 glasses) may have beneficial effects without disturbing glucose control. However, excessive alcohol consumption may have harmful effects such as hypoglycemia, impaired glucose control, metabolic dysregulation, and increased risk of diabetic complications. This review focused on the relationship between alcohol consumption and diabetic mellitus and effect of alcohol on diabetic patients. Based on previous results, we propose a theory of proper alcohol consumption in diabetic patients.</p>
</abstract>
<kwd-group xml:lang="en">
<kwd>Alcohol drinking</kwd>
<kwd>Blood glucose</kwd>
<kwd>Diabetes mellitus</kwd>
</kwd-group>
</article-meta>
</front>
<back>
<ref-list xml:lang="en">
<title>References</title>
<ref id="b1-jkd-17-41"><label>1</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Corrao</surname> <given-names>G</given-names></name> <name><surname>Bagnardi</surname> <given-names>V</given-names></name> <name><surname>Zambon</surname> <given-names>A</given-names></name> <name><surname>La Vecchia</surname> <given-names>C</given-names></name></person-group> <article-title>A metaanalysis of alcohol consumption and the risk of 15 diseases</article-title> <source>Prev Med</source> <year>2004</year><volume>38</volume> <fpage>613</fpage><lpage>9</lpage></element-citation></ref>
<ref id="b2-jkd-17-41"><label>2</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bagnardi</surname> <given-names>V</given-names></name> <name><surname>Blangiardo</surname> <given-names>M</given-names></name> <name><surname>La Vecchia</surname> <given-names>C</given-names></name> <name><surname>Corrao</surname> <given-names>G</given-names></name></person-group> <article-title>A metaanalysis of alcohol drinking and cancer risk</article-title> <source>Br J Cancer</source> <year>2001</year><volume>85</volume> <fpage>1700</fpage><lpage>5</lpage></element-citation></ref>
<ref id="b3-jkd-17-41"><label>3</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dyer</surname> <given-names>AR</given-names></name> <name><surname>Stamler</surname> <given-names>J</given-names></name> <name><surname>Paul</surname> <given-names>O</given-names></name> <name><surname>Berkson</surname> <given-names>DM</given-names></name> <name><surname>Shekelle</surname> <given-names>RB</given-names></name> <name><surname>Lepper</surname> <given-names>MH</given-names></name> <name><surname>McKean</surname> <given-names>H</given-names></name> <name><surname>Lindberg</surname> <given-names>HA</given-names></name> <name><surname>Garside</surname> <given-names>D</given-names></name> <name><surname>Tokich</surname> <given-names>T</given-names></name></person-group> <article-title>Alcohol, cardiovascular risk factors and mortality: the Chicago experience</article-title> <source>Circulation</source> <year>1981</year><volume>64</volume> <issue>III</issue> <fpage>20</fpage><lpage>7</lpage></element-citation></ref>
<ref id="b4-jkd-17-41"><label>4</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Carlsson</surname> <given-names>S</given-names></name> <name><surname>Hammar</surname> <given-names>N</given-names></name> <name><surname>Grill</surname> <given-names>V</given-names></name></person-group> <article-title>Alcohol consumption and type 2 diabetes metaanalysis of epidemiological studies indicates a U-shaped relationship</article-title> <source>Diabetologia</source> <year>2005</year><volume>48</volume> <fpage>1051</fpage><lpage>4</lpage></element-citation></ref>
<ref id="b5-jkd-17-41"><label>5</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Koppes</surname> <given-names>LL</given-names></name> <name><surname>Dekker</surname> <given-names>JM</given-names></name> <name><surname>Hendriks</surname> <given-names>HF</given-names></name> <name><surname>Bouter</surname> <given-names>LM</given-names></name> <name><surname>Heine</surname> <given-names>RJ</given-names></name></person-group> <article-title>Moderate alcohol consumption lowers the risk of type 2 diabetes: a metaanalysis of prospective observational studies</article-title> <source>Diabetes Care</source> <year>2005</year><volume>28</volume> <fpage>719</fpage><lpage>25</lpage></element-citation></ref>
<ref id="b6-jkd-17-41"><label>6</label><element-citation publication-type="book"><collab>Korea Ministry of Health and Welfare &#x0026; Korea Centers for Disease Control and Prevention</collab> <source>Korea Health Statistics 2012: Korea National Health and Nutrition Examination Survey (KNHANESV-3)</source> <publisher-loc>Cheongwon</publisher-loc> <publisher-name>Korea Centers for Disease Control and Prevention</publisher-name> <year>2014</year> <fpage>27</fpage><lpage>8</lpage></element-citation></ref>
<ref id="b7-jkd-17-41"><label>7</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Howard</surname> <given-names>AA</given-names></name> <name><surname>Arnsten</surname> <given-names>JH</given-names></name> <name><surname>Gourevitch</surname> <given-names>MN</given-names></name></person-group> <article-title>Effect of alcohol consumption on diabetes mellitus: a systematic review</article-title> <source>Ann Intern Med</source> <year>2004</year><volume>140</volume> <fpage>211</fpage><lpage>9</lpage></element-citation></ref>
<ref id="b8-jkd-17-41"><label>8</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Holbrook</surname> <given-names>TL</given-names></name> <name><surname>Barrett-Connor</surname> <given-names>E</given-names></name> <name><surname>Wingard</surname> <given-names>DL</given-names></name></person-group> <article-title>A prospective population-based study of alcohol use and non-insulindependent diabetes mellitus</article-title> <source>Am J Epidemiol</source> <year>1990</year><volume>132</volume> <fpage>902</fpage><lpage>9</lpage></element-citation></ref>
<ref id="b9-jkd-17-41"><label>9</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Seike</surname> <given-names>N</given-names></name> <name><surname>Noda</surname> <given-names>M</given-names></name> <name><surname>Kadowaki</surname> <given-names>T</given-names></name></person-group> <article-title>Alcohol consumption and risk of type 2 diabetes mellitus in Japanese: a systematic review</article-title> <source>Asia Pac J Clin Nutr</source> <year>2008</year><volume>17</volume> <fpage>545</fpage><lpage>51</lpage></element-citation></ref>
<ref id="b10-jkd-17-41"><label>10</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ajani</surname> <given-names>UA</given-names></name> <name><surname>Hennekens</surname> <given-names>CH</given-names></name> <name><surname>Spelsberg</surname> <given-names>A</given-names></name> <name><surname>Manson</surname> <given-names>JE</given-names></name></person-group> <article-title>Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians</article-title> <source>Arch Intern Med</source> <year>2000</year><volume>160</volume> <fpage>1025</fpage><lpage>30</lpage></element-citation></ref>
<ref id="b11-jkd-17-41"><label>11</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Siler</surname> <given-names>SQ</given-names></name> <name><surname>Neese</surname> <given-names>RA</given-names></name> <name><surname>Christiansen</surname> <given-names>MP</given-names></name> <name><surname>Hellerstein</surname> <given-names>MK</given-names></name></person-group> <article-title>The inhibition of gluconeogenesis following alcohol in humans</article-title> <source>Am J Physiol</source> <year>1998</year><volume>275</volume> <fpage>E897</fpage><lpage>907</lpage></element-citation></ref>
<ref id="b12-jkd-17-41"><label>12</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Vrij-Standhardt</surname> <given-names>WG</given-names></name></person-group> <article-title>Effects of alcohol on the metabolism of macronutrients</article-title> <person-group person-group-type="editor"><name><surname>Van der Heij</surname> <given-names>DG</given-names></name> <name><surname>Schaafsma</surname> <given-names>G</given-names></name></person-group> <source>Biomedical and social aspects of alcohol use: a review of the literature</source> <publisher-loc>Pudoc</publisher-loc> <publisher-name>Wageningen</publisher-name> <year>1995</year> <fpage>62</fpage><lpage>71</lpage></element-citation></ref>
<ref id="b13-jkd-17-41"><label>13</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van de Wiel</surname> <given-names>A</given-names></name></person-group> <article-title>Diabetes mellitus and alcohol</article-title> <source>Diabetes Metab Res Rev</source> <year>2004</year><volume>20</volume> <fpage>263</fpage><lpage>7</lpage></element-citation></ref>
<ref id="b14-jkd-17-41"><label>14</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van den Berg</surname> <given-names>H</given-names></name> <name><surname>van der Gaag</surname> <given-names>M</given-names></name> <name><surname>Hendriks</surname> <given-names>H</given-names></name></person-group> <article-title>Influence of lifestyle on vitamin bioavailability</article-title> <source>Int J Vitam Nutr Res</source> <year>2002</year><volume>72</volume> <fpage>53</fpage><lpage>9</lpage></element-citation></ref>
<ref id="b15-jkd-17-41"><label>15</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Halsted</surname> <given-names>CH</given-names></name> <name><surname>Villanueva</surname> <given-names>JA</given-names></name> <name><surname>Devlin</surname> <given-names>AM</given-names></name> <name><surname>Chandler</surname> <given-names>CJ</given-names></name></person-group> <article-title>Metabolic interactions of alcohol and folate</article-title> <source>J Nutr</source> <year>2002</year><volume>132</volume> <fpage>2367S</fpage><lpage>72S</lpage></element-citation></ref>
<ref id="b16-jkd-17-41"><label>16</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mukamal</surname> <given-names>KJ</given-names></name> <name><surname>Robbins</surname> <given-names>JA</given-names></name> <name><surname>Cauley</surname> <given-names>JA</given-names></name> <name><surname>Kern</surname> <given-names>LM</given-names></name> <name><surname>Siscovick</surname> <given-names>DS</given-names></name></person-group> <article-title>Alcohol consumption, bone density, and hip fracture among older adults: the cardiovascular health study</article-title> <source>Osteoporos Int</source> <year>2007</year><volume>18</volume> <fpage>593</fpage><lpage>602</lpage></element-citation></ref>
<ref id="b17-jkd-17-41"><label>17</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bush</surname> <given-names>K</given-names></name> <name><surname>Kivlahan</surname> <given-names>DR</given-names></name> <name><surname>McDonell</surname> <given-names>MB</given-names></name> <name><surname>Fihn</surname> <given-names>SD</given-names></name> <name><surname>Bradley</surname> <given-names>KA</given-names></name></person-group> <article-title>The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test</article-title> <source>Arch Intern Med</source> <year>1998</year><volume>158</volume> <fpage>1789</fpage><lpage>95</lpage></element-citation></ref>
<ref id="b18-jkd-17-41"><label>18</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Park</surname> <given-names>J</given-names></name> <name><surname>Kweon</surname> <given-names>S</given-names></name> <name><surname>Kim</surname> <given-names>Y</given-names></name> <name><surname>Jang</surname> <given-names>MJ</given-names></name> <name><surname>Oh</surname> <given-names>K</given-names></name></person-group> <article-title>Dietary behaviors related to metabolic syndrome in Korean adults</article-title> <source>Korean J Community Nutr</source> <year>2012</year><volume>17</volume> <fpage>664</fpage><lpage>75</lpage></element-citation></ref>
<ref id="b19-jkd-17-41"><label>19</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pearson</surname> <given-names>TA</given-names></name> <name><surname>Blair</surname> <given-names>SN</given-names></name> <name><surname>Daniels</surname> <given-names>SR</given-names></name> <name><surname>Eckel</surname> <given-names>RH</given-names></name> <name><surname>Fair</surname> <given-names>JM</given-names></name> <name><surname>Fortmann</surname> <given-names>SP</given-names></name> <name><surname>Franklin</surname> <given-names>BA</given-names></name> <name><surname>Goldstein</surname> <given-names>LB</given-names></name> <name><surname>Greenland</surname> <given-names>P</given-names></name> <name><surname>Grundy</surname> <given-names>SM</given-names></name> <name><surname>Hong</surname> <given-names>Y</given-names></name> <name><surname>Miller</surname> <given-names>NH</given-names></name> <name><surname>Lauer</surname> <given-names>RM</given-names></name> <name><surname>Ockene</surname> <given-names>IS</given-names></name> <name><surname>Sacco</surname> <given-names>RL</given-names></name> <name><surname>Sallis</surname> <given-names>JF</given-names> <suffix>Jr</suffix></name> <name><surname>Smith</surname> <given-names>SC</given-names> <suffix>Jr</suffix></name> <name><surname>Stone</surname> <given-names>NJ</given-names></name> <name><surname>Taubert</surname> <given-names>KA</given-names></name></person-group> <collab>American Heart Association Science Advisory and Coordinating Committee</collab> <article-title>AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases</article-title> <source>Circulation</source> <year>2002</year><volume>106</volume> <fpage>388</fpage><lpage>91</lpage></element-citation></ref>
<ref id="b20-jkd-17-41"><label>20</label><element-citation publication-type="book"><collab>Korean Dietetic Association</collab> <article-title>Liver, gallbladder and pancreatitis disease</article-title> <collab>Korean Dietetic Association</collab> <source>Manual of medical nutrition therapy</source> <edition>3rd ed.</edition> <publisher-loc>Seoul</publisher-loc> <publisher-name>Medrang</publisher-name> <year>2008</year> <comment>p221.</comment></element-citation></ref>
</ref-list>
</back>
</article>
