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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
<article xml:lang="EN" article-type="case-report">

<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Cardiovasc Ultrasound</journal-id>
<journal-id journal-id-type="publisher-id">JCU</journal-id>
<journal-title-group>
<journal-title>Journal of Cardiovascular Ultrasound</journal-title>
</journal-title-group>
<issn pub-type="ppub">1975-4612</issn>
<issn pub-type="epub">2005-9655</issn>
<publisher>
<publisher-name>Korean Society of Echocardiography</publisher-name>
</publisher>
</journal-meta>

<article-meta>
<article-id pub-id-type="doi">10.4250/jcu.2015.23.3.191</article-id>
<article-categories>
<subj-group>
<subject>Images in Cardiovascular Ultrasound</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Blooming Flower in Misty Left Atrium</article-title>
</title-group>

<contrib-group>

<contrib contrib-type="author" corresp="yes">
<name>
<surname>Tarikere Hemaraju</surname>
<given-names>Shivashankara</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>

<contrib contrib-type="author">
<name>
<surname>Ali</surname>
<given-names>Amjad</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>

<contrib contrib-type="author">
<name>
<surname>Cholenahally Nanjappa</surname>
<given-names>Manjunath</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1"></xref>
</contrib>

</contrib-group>

<aff id="A1">Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Research and Sciences, Bangalore, India.</aff>

<author-notes>
<corresp>
Address for Correspondence: Shivashankara Tarikere Hemaraju, Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Research and Sciences, Jaya Nagar 9th Block, BG Road, Bangalore 560069, Karnataka, India. Tel: +91-9241675034, Fax: +91-8026534477, <email>drshivashankarath@gmail.com</email>
</corresp>
</author-notes>

<pub-date pub-type="ppub">
<month>09</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub">
<day>24</day>
<month>09</month>
<year>2015</year>
</pub-date>
<volume>23</volume>
<issue>3</issue>
<fpage>191</fpage>
<lpage>192</lpage>

<history>
<date date-type="received">
<day>01</day>
<month>03</month>
<year>2015</year>
</date>
<date date-type="rev-recd">
<day>01</day>
<month>04</month>
<year>2015</year>
</date>
<date date-type="accepted">
<day>22</day>
<month>07</month>
<year>2015</year>
</date>
</history>

<permissions>
<copyright-statement>Copyright &#x00A9; 2015 Korean Society of Echocardiography</copyright-statement>
<copyright-year>2015</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>

<kwd-group>
<kwd>Left atrial thrombus</kwd>
<kwd>Mitral stenosis</kwd>
<kwd>Transesophageal echocardiography</kwd>
</kwd-group>

</article-meta>
</front>

<body>

<p>Left atrial (LA) thrombus is known as a common complication of rheumatic mitral stenosis. It is more common in the presence of atrial fibrillation (AF). Incidence of LA clot formation in sinus rhythm is 2.4-13.5&#x0025;<xref ref-type="bibr" rid="B1">1)</xref><xref ref-type="bibr" rid="B2">2)</xref> and the incidence is as high as 33&#x0025; in patients with mitral stenosis in AF. Because transthoracic echocardiography may not detect the left atrial appendage (LAA) thrombus, transesophageal echocardiography (TEE) remains the gold standard for identifying the LAA thrombus. We report a case of LAA thrombus mimicking like a hydatid cyst. A 38 years old male with severe mitral stenosis due to rheumatic heart disease presented with progressive worsening of dyspnea (New York Heart Association class II-III) over a period of two years. The electrocardiogram revealed sinus rhythm with evidence of LA enlargement. There was no past history of AF and he was not on any anticoagulants. The transthoracic echocardiogram revealed thickened mitral leaflets with mitral orifice area of 1.0 cm<sup>2</sup> and mean mitral valve gradient of 18 mm Hg. The LA was enlarged and there was grade IV spontaneous echo contrast in LA. On TEE, there was large cystic mobile formation noted in the LA, originating from LAA and protruding into LA body. Nodular structures were visible within the cystic formation (<xref ref-type="fig" rid="F1">Fig. 1</xref>, <xref ref-type="supplementary-material" rid="S1">Supplementary movie 1</xref>). In four-chamber view at 0&#x00B0;, it was appearing like a blooming flower (<xref ref-type="fig" rid="F2">Fig. 2</xref>, <xref ref-type="supplementary-material" rid="S2">Supplementary movie 2</xref>). Thrombus is identified by the homogenous echo texture and visualised in more than one plane. It can appear in various forms and shapes depending on the organisation of clot.</p>

<p>TEE is a useful tool to detect LA thrombus in patients with mitral stenosis. The clot in LA can occur in various forms from cystic lesions to mass like appearences. One should look for LAA clot in cases of rheumatic mitral stenosis before subjecting for balloon mitral valvotomy whether patients are in AF or sinus rhythm. In the presence of high grade of spontanous echo contrast, LA clot should be always suspected.<xref ref-type="bibr" rid="B3">3)</xref></p>

</body>

<back>

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<sec sec-type="supplementary-material">

<title>Supplementary Material</title>
<supplementary-material id="S1" content-type="local-data">
<caption>
<title>Movie 1</title>
<p>Cystic mass arising from left atrial appendage with nodular structures inside it.</p>
</caption>
<media mimetype="application" mime-subtype="avi" xlink:href="jcu-23-191-s001.avi"/>
</supplementary-material>

<supplementary-material id="S2" content-type="local-data">
<caption>
<title>Movie 2</title>
<p>Nodular structures within cystic formation mimicking hydatid cyst in left atrium.</p>
</caption>
<media mimetype="application" mime-subtype="avi" xlink:href="jcu-23-191-s002.avi"/>
</supplementary-material>
</sec>


</back>

<floats-group>

<fig position="float" id="F1">
<label>Fig. 1</label>
<caption>
  <title>Cystic mass arising from left atrial appendage with nodular structures inside it.</title>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jcu-23-191-g001"></graphic>
</fig>

<fig position="float" id="F2">
<label>Fig. 2</label>
<caption>
  <title>Arrow showing nodular structures within cystic formation mimicking hydatid cyst in left atrium.</title>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="jcu-23-191-g002"></graphic>
</fig>

</floats-group>

</article>