JKOS Journal of the Korean Ophthalmological Society J Korean Ophthalmol Soc 0378-6471 2092-9374 Korean Ophthalmological Society 10.3341/jkos.2017.58.1.83 jkos-58-83 Original Article A Case of Upper Eyelid Schwannoma YangHeon M.D RohJoo Heon M.D Sungmo Eye Hospital, Busan, Korea Address reprint requests to Joo Heon Roh, MD Sungmo Eye Hospital, #409 Haeun-daero, Haeundae-gu, Busan 48064, Korea Tel: 82-51-743-0775, Fax: 82-51-743-0776 E-mail: rhoahn12@gmail.com 08 2017 30 8 2017 58 1 83 86 14 7 2016 8 9 2016 27 12 2016 Copyright © 2017 Korean Ophthalmological Society 2017 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Purpose

To report a rare case of upper eyelid schwannoma presenting as a chalazion.

 Case summary

A 54-year-old male presented to our clinic with a slowly growing, painless recurred mass located in the middle area of the right upper eyelid margin. Surgical incision had been performed on a similar mass two year previous, although no his-tological analysis had been performed. On examination, a 4 × 3-mm-sized, firm, nonpigmented mass was palpable in the right upper eyelid, and no signs of neurofibromatosis were present elsewhere. The lesion was initially thought to be an eyelid mass, so we performed an excisional biopsy under local anesthesia. The lesion was easily isolated from the surrounding tissue and was excised completely. Histopathologically, the excised mass showed a compact arrangement of spindle cells forming pal-isades with Verocay bodies (Antoni A patterns). Immunohistochemistry revealed diffuse and strong S-100 protein positivity. These findings resulted in the diagnosis of eyelid schwannoma.

 Conclusions

Because of its rarity and solitary feature, eyelid schwannoma can be confused with chalazion. Thus, ophthalmolo-gists should consider schwannoma in the differential diagnosis of a slowly growing, painless recurred mass or a lesion with ma-lignant transformation after incomplete excision.

 Eyelid Schwannoma References Welch,RBDukeJRLesions of the lids: a statistical noteAm J Ophthalmol19616611124 AllingtonHVAllingtonJHEyelid tumorsArch Dermatol19616611124 SidiquiMALeslieTScottCMackenzieJEyelid schwannoma in a male adultClin Exp Ophthalmol19616611124 ChungYRMoonSJangJWEyelid schwannoma in a Korean womanJpn J Ophthalmol19616611124 BaijalGCGargSKKanhereSMongaSSchwannoma of the eye-lidIndian J Ophthalmol19616611124 ButtZIronsideJWSuperficial epitheloid schwannoma present-ing as a subcutaneous upper eyelid massBr J Ophthalmol19616611124 GelincikIRight upper eyelid schwannoma in a child: a case reportJ Clin Exp Pathol201221000116 ShieldsJAGuiborPNeurilemoma of the eyelid resembling a re-current chalazionArch Ophthalmol19841021650 ShieldsJAKiratliHShieldsCLSchwannoma of the eyelid in a childJ Pediatr Ophthalmol Strabismus19616611124 López-TizónEMencía-GutiérrezEGutiérrez-DíazERicoyJRSchwannoma of the eyelid: report of two casesDermatol Online J20071312 LeeKWLeeMJKimNJA case of eyelid schwannomaJ Korean Ophthalmol Soc19616611124 YuichiOTatsuoYA case of schwannoma in the upper eyelidJ Eye Ophthalmic Plast Reconstr Surg19616611124 KumarSKumarSKulshresthaRCystic schwannoma of eyelid in an Indian male: a rare presentationOrbit19616611124 SinghSSarafSGoswamiDSinghSCase report of isolated schwannoma‑ a rare eyelid tumorUS Ophthalmic Review,201471435 MagdumRMParanjpeRKotechaMPatilPSolitary eyelid schwannomaMed J DY Patil Univ19616611124 RootmanJGoldbergCRobertsonWPrimary orbital schwan-nomasBr J Ophthalmol19616611124 Le Marc’hadourFRomanetJPFdiliASchwannoma of the bulbar conjunctivaArch Ophthalmol19616611124 ShieldsJAFontRLEagleRCJrMelanotic schwannoma of the choroid: immunohistochemistry and electron microscopic observationsOphthalmology19616611124 GrahamCMMcCartneyACBuckleyRJIntrascleral neuril-emmomaBr J Ophthalmol19616611124 Figures

Clinical photograph of the right eye. Preoperative photograph shows a 4 × 3 mm-sized non-pigmented chala-zion-like mass on the right upper eyelid margin.

Light micrograph of excisional biopsy specimen. (A) The Antoni type A area shows cellular proliferation of spindle cells arranged in a palisading fashion (red arrows). In this case, type B area is not identified (hematoxylin-eosin, ×400). (B) Immunostaining for S100 protein is strong and dif-fuse (S-100, ×400).

Clinical photograph of the right eye at 8 weeks after excision. Postoperative photograph showed removed site was clear. No recurrence was observed.