JKOS Journal of the Korean Ophthalmological Society J Korean Ophthalmol Soc 0378-6471 2092-9374 The Korean Society for Quality Management 10.3341/jkos.2015.56.7.998 jkos-56-998 Original Article Assessment of Posterior Capsular Opacification of Korean Using Straylight and Glare Sensitivity Meter ChoiSeung Yong M.D ParkYu Li M.D KimHyun Seung M.D, PhD Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea Address reprint requests to Hyun Seung Kim, MD, PhD Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital, #10 63-ro, Yeongdeungpo-gu, Seoul 150-713, Korea Tel: 82-2-3379-1243, Fax: 82-2-761-6869 E-mail: Sara514@catholic.ac.kr 08 2015 27 8 2015 56 7 998 1004 02 10 2014 24 01 2015 26 05 2015 Copyright © 2015 Korean Ophthalmological Society 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Purpose:

To evaluate posterior capsular opacity (PCO) using straylight and glare sensitivity meter and to compare availability of straylight and glare sensitivity with known methods for PCO evaluation.

 Methods:

Thirty-six pseudophakic eyes with PCO were selected for this study. Best-corrected visual acuity (BCVA), straylight (C-quant, Oculus GmbH, Wetzlar, Germany) and glare sensitivity (Binoptometer, Oculus GmbH, Wetzlar, Germany) were meas-ured before mydriasis. After mydriasis, PCO images were captured with a slit-lamp and analyzed using the Evaluation of Posterior Capsular Opacification (EPCO) program (EPCO software, University of Heidelberg, Heidelberg, Germany). The same measurements were taken after capsulotomy and compared with pre-capsulotomy data.

 Results:

After capsulotomy, BCVA, EPCO score and straylight were improved with statistical significance ( p < 0.05). Cases of PCO with mildly decreased visual acuity showed statistically significantly improved EPCO score and straylight ( p < 0.05). Glare sensitivity did not show significant improvement but was statistically significantly correlated with straylight ( p = 0.023, Rho = 0.732).

 Conclusions:

Straylight is an available measurement for evaluation of PCO. Glare sensitivity meter which correlates with stray-light can be used as a supportive measurement.

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Compensation method of C-quant and test field. (A) Stray light source on state. From outermost circle zone, projection of stray light source is scattered to the retina including fovea. (B) Stray light source off state. From innermost circle zone, compensa-tion light flickering is projected to fovea. (C) Real test field. Zone a is stray light source and zone b is compensation light source. * Outermost circle zone; † Innermost circle zone.

Test field of glare sensitivity meter. (A) Light source off state. Randolt ring of resolution of 0.1 arc-minute is shown. (B) Light source on state. Brightness is increased and contrast is decreased due to glare light source.

Image of posterior capsular opacity from slit-lamp camera (A) and analyzed image by Evaluation of Posterior Capsular Opacification (EPCO) software (B).

Comparison of mean and 95% confidence interval (CI) of measurement in preYAG (Pre-YAG capsulotomy state) and postYAG (Post-YAG capsulotomy state) of total participants. (A) Best corrected visual acuity (BCVA) improved from 0.49 ± 0.25 to 0.77 ± 0.20. (B) Log(s) of stray light improved from 1.79 ± 0.62 to 1.45 ± 0.18. (C) Evaluation of Posterior Capsular Opacification (EPCO) score improved from 0.44 ± 0.48 to 0.04 ± 0.03. All measurements improved with statistical significance ( p = 0.001, p = 0.001, p = 0.018, respectively).

Comparison of mean and 95% confidence interval (CI) of measurement in preYAG (Pre-YAG capsulotomy state) and postYAG (Post-YAG capsulotomy state) of participants whose pre-capsulotomy visual acuity was equal or better than 0.63. (A) Best corrected visual acuity (BCVA) are improved from 0.76 ± 0.13 to 0.86 ± 0.09 without statistical significance ( p = 0.061). (B) Log(s) of stray light improved from 1.57 ± 0.18 to 1.29 ± 0.04 and (C) Evaluation of Posterior Capsular Opacification (EPCO) score improved from 0.22 ± 0.12 to 0.04 ± 0.03. Both measurements showed statistically significant improvement ( p = 0.018, p = 0.043, respectively).

(A) Comparison of glare sensitivity before and after capsulotomy. Glare sensitivity decreased from 0.055 ± 0.083 to 0.038 ± 0.052 without statistically significant improvement. (B) Statistical dispersion of glare sensitivity with stray light. It shows statistically significant correlation with stray light ( p = 0.023, Rho = 0.732). CI = confidence interval; PreYAG =Pre-YAG cap-sulotomy state; PostYAG =Post-YAG capsulotomy state.

Demographics and measured data

No. of patients (eyes) 36
Age (years) 66.7 ± 10.9
Sex (Male:female) 6:30
Mean interval (months)∗ 24.6 ± 15.1
BCVA
 Pre-capsulotomy 0.49 ± 0.25
 Post-capsulotomy ( p-value) 0.77 ± 0.20 ( p < 0.001)
Log(s) of Straylight
 Pre-capsulotomy 1.79 ± 0.62
 Post-capsulotomy ( p-value) 1.45 ± 0.18 ( p = 0.001)
EPCO score
 Pre-capsulotomy 0.44 ± 0.48
 Post-capsulotomy ( p-value) 0.04 ± 0.03 ( p = 0.018)
Log CS of glare sensitivity
 Pre-capsulotomy 0.055 ± 0.083
 Post-capsulotomy ( p-value) 0.038 ± 0.052 ( p = 0.273)

Values are presented as mean ± SD unless otherwise indicated. BCVA = best corrected visual acuity; EPCO = Evaluation of Posterior Capsular Opacification.

Mean interval from cataract operation to neodymium-doped yttrium aluminium garnet (Nd:YAG) capsulotomy.