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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "JATS-journalpublishing1.dtd">
<article article-type="research-article" dtd-version="1.0" xml:lang="en" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">JKOS</journal-id>
<journal-title-group>
<journal-title>Journal of the Korean Ophthalmological Society</journal-title>
<abbrev-journal-title>J Korean Ophthalmol Soc</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">0378-6471</issn>
<issn pub-type="epub">2092-9374</issn>
<publisher>
<publisher-name>Korean Ophthalmological Society</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3341/jkos.2010.51.2.169</article-id>
<article-id pub-id-type="publisher-id">jkos-51-169</article-id>
<article-categories>
<subj-group>
<subject>Original Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Measurement of White-to-White Diameter and Anterior Chamber Depth by Dual Scheimpflug Camera</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en"><surname>Han</surname><given-names>Kyung-Eun</given-names></name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="aff1-jkos-51-169"/>
</contrib>
<contrib contrib-type="author">
<name name-style="western" xml:lang="en"><surname>Jun</surname><given-names>Roo Min</given-names></name>
<degrees>MD, PhD</degrees>
<xref ref-type="corresp" rid="c1-jkos-51-169"/>
<xref ref-type="aff" rid="aff1-jkos-51-169"/>
</contrib>
<aff id="aff1-jkos-51-169" xml:lang="en">Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, <country>Korea</country></aff>
</contrib-group>
<author-notes>
<corresp id="c1-jkos-51-169">Address reprint requests to <bold>Roo Min Jun, MD</bold> Department of Ophthalmology, Ewha Womans University School of Medicine, Mok-dong Hospital &#x0023;911-1 Mok-dong, Yangcheon-gu, Seoul 158-710, Korea Tel: 82-2-2650-5154, Fax: 82-2-2654-4334, E-mail: <email>jrmoph@ewha.ac.kr</email></corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>09</month>
<year>2010</year>
</pub-date>
<pub-date pub-type="epub">
<day>07</day>
<month>09</month>
<year>2010</year>
</pub-date>
<volume>51</volume>
<issue>2</issue>
<fpage>169</fpage>
<lpage>174</lpage>
<history>
<date date-type="received"><day>04</day><month>03</month><year>2009</year></date>
<date date-type="accepted"><day>29</day><month>10</month><year>2009</year></date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2010 Korean Ophthalmological Society</copyright-statement>
<copyright-year>2010</copyright-year>
<license><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license>
</permissions>
<abstract xml:lang="en">
<title>Abstract</title>
<sec>
<title>Purpose</title>
<p>To estimate the horizontal and vertical white-to-white diameters (WTW) and anterior chamber depths (ACD) with a dual Scheimpflug camera (GALILEI&#x2122;, Ziemer, Switzerland) and to compare the estimates measured by a measuring caliper and ultrasound biomicroscopy (UBM PlusTM, Paradigm Inc., Utah, USA) in normal subjects.</p>
</sec>
<sec>
<title>Methods</title>
<p>Forty-four eyes of 23 subjects were evaluated. Corneal diameter as measured by GALILEI was directly compared with the white-to-white diameter (WTW) measured by a caliper and the correlation with ciliary sulcus diameter (STS) by UBM was evaluated. The anterior chamber depth (ACD) as measured by GALILEI&#x2122; was compared with the estimates measured by UBM.</p>
</sec>
<sec>
<title>Results</title>
<p>The horizontal and vertical diameters of WTW by GALILEI were not significantly different from the measurements taken by calipers (<italic>p</italic>&#x003E;0.05, <italic>p</italic>&#x003E;0.05, respectively), and there were no correlations between the measurements (<italic>r</italic>&#x003D;-0.074, <italic>p</italic>&#x003E;0.05 at 180 <sup>o</sup> r&#x003D;0.297, p&#x003E;0.05 at 90 <sup>o</sup>, respectively). The estimates by GALILEI did not correlate with those measured with UBM (<italic>r</italic>&#x003D;-0.006, <italic>p</italic>&#x003E;0.05 at 180 <sup>o</sup> <italic>r</italic>&#x003D;-0.222, <italic>p</italic>&#x003E;0.05 at 90 <sup>o</sup>, respectively). However, the mean ACD by GALILEI was deeper than thatby UBM (<italic>p</italic>&#x003C;0.01), and the measurements correlated strongly with each other (<italic>r</italic>&#x003D;0.760; <italic>p</italic>&#x003C;0.01).</p>
</sec>
<sec>
<title>Conclusions</title>
<p>The mean WTW measured by GALILEI was not significantly different from the measurements taken by calipers and the measurements did not correlate with each other. There was also no correlation with the measurementsby GALILEI and UBM. ACD by GALILEI was measured to be deeper those that by UBM.</p>
</sec>
</abstract>
<kwd-group xml:lang="en">
<kwd>Anterior chamber depth</kwd>
<kwd>GALILEI</kwd>
<kwd>Scheimpflug camera</kwd>
<kwd>Sulcus diameter</kwd>
<kwd>White-to-white diameter</kwd>
</kwd-group>
</article-meta>
</front>
<back>
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<sec sec-type="display-objects">
<title>Figures and Tables</title>
<fig id="f1-jkos-51-169" position="anchor">
<label>Figure 1.</label>
<caption xml:lang="en"><p>Scatter plot of horizontal (A) and vertical (B) WTW measured by calipers and GALILEI <sup>TM</sup>.</p></caption>
<graphic xlink:href="jkos-51-169f1.tif"/>
</fig>
<fig id="f2-jkos-51-169" position="anchor">
<label>Figure 2.</label>
<caption xml:lang="en"><p>Scatter plot of horizontal (A) and vertical (B) WTW measured by GALILEI <sup>TM</sup> and UBM.</p></caption>
<graphic xlink:href="jkos-51-169f2.tif"/>
</fig>
<fig id="f3-jkos-51-169" position="anchor">
<label>Figure 3.</label>
<caption xml:lang="en"><p>Scatter plot of ACD measured by GALILEI <sup>TM</sup> and UBM. ACD&#x003D;anterior chamber depth.</p></caption>
<graphic xlink:href="jkos-51-169f3.tif"/>
</fig>
<table-wrap id="t1-jkos-51-169" position="float">
<label>Table 1.</label>
<caption xml:lang="en"><p>Demographics of patients (Mean&#x00B1; SD)</p></caption>
<table rules="groups" frame="hsides">
<thead>
<tr>
<th valign="middle" align="center">Characteristics</th>
<th valign="middle" align="center">Values</th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">No. of patients (eyes)</td>
<td valign="middle" align="center">23 (44)</td>
</tr>
<tr>
<td valign="middle" align="left">Sex (M:F)</td>
<td valign="middle" align="center">4:19</td>
</tr>
<tr>
<td valign="middle" align="left">Ages (years)</td>
<td valign="middle" align="center">30.2&#x00B1;7.44</td>
</tr>
<tr>
<td valign="middle" align="left">Spherical equivalent (diopter)</td>
<td valign="middle" align="center">&#x2212;2.74&#x00B1;1.94</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap id="t2-jkos-51-169" position="float">
<label>Table 2.</label>
<caption xml:lang="en"><p>Comparison of estimates by calipers, GALILEI <sup>TM</sup> and UBM (Mean&#x00B1; SD)</p></caption>
<table rules="groups" frame="hsides">
<thead>
<tr>
<th valign="middle" align="center">&#xE251;</th>
<th valign="middle" align="center">Caliper (WTW<sup><xref ref-type="table-fn" rid="table2-fn2-jkos-51-169">&#x2020;</xref></sup>)</th>
<th valign="middle" align="center">GALILEI (WTW)</th>
<th valign="middle" align="center">UBM (STS<sup><xref ref-type="table-fn" rid="table2-fn3-jkos-51-169">&#x2021;</xref></sup>)</th>
<th valign="middle" align="center"><italic>p</italic>-value<sup><xref ref-type="table-fn" rid="table2-fn1-jkos-51-169">&#x002A;</xref></sup></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">Horizontal (mm)</td>
<td valign="middle" align="center">11.6&#x00B1;0.50</td>
<td valign="middle" align="center">11.3&#x00B1;1.18</td>
<td valign="middle" align="center">11.0&#x00B1;0.89</td>
<td valign="middle" align="center">0.111</td>
</tr>
<tr>
<td valign="middle" align="left">Vertical (mm)</td>
<td valign="middle" align="center">11.2&#x00B1;0.51</td>
<td valign="middle" align="center">11.5&#x00B1;1.10</td>
<td valign="middle" align="center">11.1&#x00B1;0.92</td>
<td valign="middle" align="center">0.138</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table2-fn1-jkos-51-169"><label>&#x002A;</label><p>Paired t-test in caliper and GALILEI</p></fn>
<fn id="table2-fn2-jkos-51-169"><label>&#x2020;</label><p>WTW&#x003D;white-to-white diameter</p></fn>
<fn id="table2-fn3-jkos-51-169"><label>&#x2021;</label><p>STS&#x003D;ciliary sulcus diameter.</p></fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="t3-jkos-51-169" position="float">
<label>Table 3.</label>
<caption xml:lang="en"><p>Comparison of the anterior chamber depth (ACD) by GALILEI <sup>TM</sup> and UBM (Mean&#x00B1; SD)</p></caption>
<table rules="groups" frame="hsides">
<thead>
<tr>
<th valign="middle" align="center">Measurement</th>
<th valign="middle" align="center">GALILEI</th>
<th valign="middle" align="center">UBM</th>
<th valign="middle" align="center">p-value<sup><xref ref-type="table-fn" rid="table3-fn1-jkos-51-169">&#x002A;</xref></sup></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="middle" align="left">ACD (mm)</td>
<td valign="middle" align="center">3.1 &#x00B1;0.29</td>
<td valign="middle" align="center">2.9 &#x00B1; 0.28</td>
<td valign="middle" align="center">&#x003C;0.01</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="table3-fn1-jkos-51-169"><label>&#x002A;</label><p>Paired <italic>t</italic>-test.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
</back>
</article>
