The Association between Sitting Time, Physical Activity Level and Chronic Kidney Disease in the Healthy Adults

Park, Doo Yong; Lee, On; Kim, Yeon Soo

doi:10.5763/kjsm.2017.35.1.32

Clinical Article

Open Access


Korean J Sports Med. 2017 Jun;35(1):32-39. Korean. Published online June 07, 2017. https://doi.org/10.5763/kjsm.2017.35.1.32
Copyright © 2017 The Korean Society of Sports Medicine


The Association between Sitting Time, Physical Activity Level and Chronic Kidney Disease in the Healthy Adults
Doo Yong Park, On Lee, and Yeon Soo Kim
Department of Physical Education, Seoul National University, Seoul, Korea.
Correspondence: On Lee. Department of Physical Education, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea. Tel: +82-2-880-7794, Fax: +82-2-886-7804, Email: fair98@snu.ac.kr

Received December 09, 2016; Revised April 13, 2017; Accepted April 19, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Go to: Abstract
This study aimed to examine the prevalence of chronic kidney disease (CKD) in association with physical activity and sitting time. Participants of this study are Korean men and women aged 40 to 69, who completed health examination from 2001 to 2003. Physical activity was measured by using an International Physical Activity questionnaire. CKD was defined by estimated glomerular filtration rate that is lower than 60 mL/min/1.73 m². Logistic regression was conducted to evaluate the association of sitting time and physical activity with CKD (p<0.05). When age, sex, and other risk factor of CKD are adjusted, subjects who reported high level of physical activity participation had a significantly lower odds ratio (OR) of CKD than subjects who reported as sitting low level of physical activity participation (OR, 0.70; 95% confidence interval [CI], 0.50–0.99), and subjects who spend more than 5 hours had significantly higher OR of CKD than subjects who spend less than 1 hours (OR, 1.63; 95% CI, 1.13–2.37). Multivariate-adjusted OR of CKD associated with sitting time more than 5 hours (OR, 2.21; 95% CI, 1.09–4.52) and high physical activity participation more than 1 hours (OR, 0.48; 95% CI, 0.23–0.99) and 5 hours (OR, 0.47; 95% CI, 0.24–0.90) were significant in men. High level of physical activity and low level of sitting time were independently associated with OR of CKD, and this supports the importance of reducing sitting time as well as promoting physical activity participation.


Keywords: Sedentary lifestyle; Physical activity; Chronic kidney disease

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Tables


	Table 1 Baseline characteristics of study participants by gender
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	Table 2 Association of sedentary behavior and physical activity with CKD in healthy adult
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	Table 3 Association of sedentary behavior physical activity with CKD in healthy adult by gender
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Notes

Conflict of Interest:No potential conflict of interest relevant to this article was reported.

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References


1.	Healy GN, Wijndaele K, Dunstan DW, et al. Objectively measured sedentary time, physical activity, and metabolic risk: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Diabetes Care 2008;31:369–371.

2.	Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea Health Statistics 2015: Korea National Health and Nutrition Examination Survey (KNHANES VI-3). Cheongju: Korea Centers for Disease Control and Prevention; 2015.

3.	Thyfault JP, Du M, Kraus WE, Levine JA, Booth FW. Physiology of sedentary behavior and its relationship to health outcomes. Med Sci Sports Exerc 2015;47:1301–1305.

4.	Guo V, Brage S, Ekelund U, Griffin S, Simmons RK. ADDITION-Plus Study Team. Objectively measured sedentary time, physical activity and kidney function in people with recently diagnosed type 2 diabetes: a prospective cohort analysis. Diabet Med 2016;33:1222–1229.

5.	Chronic Kidney Disease Prognosis Consortium. Matsushita K, van der Velde M, et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010;375:2073–2081.

6.	Astor BC, Matsushita K, Gansevoort RT, et al. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease: a collaborative meta-analysis of kidney disease population cohorts. Kidney Int 2011;79:1331–1340.

7.	Beddhu S, Baird BC, Zitterkoph J, Neilson J, Greene T. Physical activity and mortality in chronic kidney disease (NHANES III). Clin J Am Soc Nephrol 2009;4:1901–1906.

8.	Levey AS, Coresh J. Chronic kidney disease. Lancet 2012;379:165–180.

9.	Park JI, Baek H, Jung HH. Prevalence of chronic kidney disease in Korea: the Korean National Health and Nutritional Examination Survey 2011-2013. J Korean Med Sci 2016;31:915–923.

*10.*	Gould DW, Graham-Brown MP, Watson EL, Viana JL, Smith AC. Physiological benefits of exercise in pre-dialysis chronic kidney disease. Nephrology (Carlton) 2014;19:519–527.

*11.*	Carney EF. Chronic kidney disease: walking reduces inflammation in predialysis CKD. Nat Rev Nephrol 2014;10:300.

*12.*	Robinson-Cohen C, Katz R, Mozaffarian D, et al. Physical activity and rapid decline in kidney function among older adults. Arch Intern Med 2009;169:2116–2123.

*13.*	Chen IR, Wang SM, Liang CC, et al. Association of walking with survival and RRT among patients with CKD stages 3-5. Clin J Am Soc Nephrol 2014;9:1183–1189.

*14.*	Garcia LM, da Silva KS, Del Duca GF, da Costa FF, Nahas MV. Sedentary behaviors, leisure-time physical inactivity, and chronic diseases in Brazilian workers: a cross sectional study. J Phys Act Health 2014;11:1622–1634.

*15.*	Lynch BM, White SL, Owen N, et al. Television viewing time and risk of chronic kidney disease in adults: the AusDiab Study. Ann Behav Med 2010;40:265–274.

*16.*	Bharakhada N, Yates T, Davies MJ, et al. Association of sitting time and physical activity with CKD: a cross-sectional study in family practices. Am J Kidney Dis 2012;60:583–590.

*17.*	Bowlby W, Zelnick LR, Henry C, et al. Physical activity and metabolic health in chronic kidney disease: a cross-sectional study. BMC Nephrol 2016;17:187.

*18.*	Stengel B, Tarver-Carr ME, Powe NR, Eberhardt MS, Brancati FL. Lifestyle factors, obesity and the risk of chronic kidney disease. Epidemiology 2003;14:479–487.

*19.*	Yoon J, Kim KK, Hwang IC, Lee KS, Suh HS. Association between body mass index, abdominal obesity defined by waist circumference criteria, and estimated glomerular filtration rate in healthy Korean adults: 2007 the Korea National Health and Nutrition Survey. Korean J Obes 2011;20:202–209.

*20.*	Hu B, Liu X, Wang C, et al. Vigorous-intensity physical activity is associated with metabolic syndrome among the Chinese middle-aged population: a cross-sectional study. Int J Sport Nutr Exerc Metab 2015;25:119–127.

*21.*	Jafar TH, Jin A, Koh WP, Yuan JM, Chow KY. Physical activity and risk of end-stage kidney disease in the Singapore Chinese Health Study. Nephrology (Carlton) 2015;20:61–67.

*22.*	Assah FK, Brage S, Ekelund U, Wareham NJ. The association of intensity and overall level of physical activity energy expenditure with a marker of insulin resistance. Diabetologia 2008;51:1399–1407.

*23.*	Hamburg NM, McMackin CJ, Huang AL, et al. Physical inactivity rapidly induces insulin resistance and microvascular dysfunction in healthy volunteers. Arterioscler Thromb Vasc Biol 2007;27:2650–2656.

*24.*	Schrage WG. Not a search in vein: novel stimulus for vascular dysfunction after simulated microgravity. J Appl Physiol (1985) 2008;104:1257–1258.