Journal List > Korean J Gastroenterol > v.69(3) > 1007624

Lee, Park, Kim, Seo, You, Chung, Moon, and Hong: A Case of Endoscopically Treated Laryngopharyngitis Resulting from Clinostomum complanatum Infection

Abstract

A 46-year-old woman visited our hospital presenting throat pain and globus sensation. The symptoms occurred seven days after eating raw perch and mullet. An endoscopy under sedation showed a fluke― with an approximate length of 4.8 mm and width of 1.5 mm― on the left aryepiglottic fold, with active motility on the mucosa. It was extracted from the larynx using biopsy forceps and was identified as Clinostomum complanatum. To the best of our knowledge, this is the second reported case of human infection with Clinostomum complanatum diagnosed and treated by an endoscopy in Korea. Endoscopy is a useful tool in the diagnosis and treatment of patients at risk for parasitic infections complaining of throat pain.

References

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Fig. 1.
(A, B) Endoscopy shows the entire Clinostomum complanatum organism (black arrow) on the lateral side of the left aryepiglottic fold. (B– E) The fluke is approximately 5 mm in length and 2 mm in width, and it was torn during the removal procedure. (F) After removal, small mucosal petechiae are observed in the affected area, but neither active bleeding nor mucosal defects are observed.
kjg-69-177f1.tif
Fig. 2.
(A) Histological sections of the fluke show a characteristic distribution of internal organs for Clinostomum complanatum. The two testes are roughly triangular. The posterior testis is a rounded triangular shape and anteriorly concave. A part of the uterus containing eggs is positioned between the anterior and posterior testes. The ovary is placed laterally to the uterus. The numerous follicular vitellaria are distributed along the lateral margins of the posterior half of the body. Two intestinal ceca (white arrows) run posteriorly, containing digested materials that are stained brown and dark gray in color (H&E stain, ×40). (B) Histological examination demonstrates the tegument with the many filamentous materials (H&E stain, ×400). Ta, anterior testis; U, uterus; Tp, posterior testis.
kjg-69-177f2.tif
Table 1.
Summary of Clinostomum complanatum Infections in Korea
Case no. Study Age(yr)/ Sex Site of infection Symptoms (Duration, day) Food Removal method
1 Chung et al. (1995)4 56/M Pharynx Throat pain (3–4 d) Fresh-water fish Otolaryngological removal
2 Park et al. (2009)5 33/M Larynx Throat pain (7–8 d) Perch Endoscopic removal
3 Jung et al. (2015)6 13/F Nasopharynx Globus sensation (4 d) Mullet Surgical removal
4 Present case 46/F Larynx (AEF) Throat pain, globus sensation (7d) Perch, Mullet Endoscopic removal

AEF, aryepiglottic fold.

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