Primary Neuroendocrine Tumor of the Extrahepatic Bile Duct

Jun Hyuk Son; Yoon Suk Lee; Yong Chan Shin; Han-Seong Kim

doi:10.4166/kjg.2018.72.4.222

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Son, Lee, Shin, and Kim: Primary Neuroendocrine Tumor of the Extrahepatic Bile Duct

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The Korean Journal of Gastroenterology 2018; 72(4): 222-225.

Published online: 30 October 2018

DOI: https://doi.org/10.4166/kjg.2018.72.4.222

Primary Neuroendocrine Tumor of the Extrahepatic Bile Duct

Jun Hyuk Son, Yoon Suk Lee

, Yong Chan Shin¹, Han-Seong Kim²

Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.

¹Department of Surgery, Inje University Ilsan Paik Hospital, Goyang, Korea.

²Department of Pathology, Inje University Ilsan Paik Hospital, Goyang, Korea.

Correspondence to: Yoon Suk Lee, Department of Internal Medicine, Inje University Ilsan Paik Hospital, 170 Juhwa-ro, Ilsanseo-gu, Goyang 10380, Korea. Tel: +82-31-910-7797, Fax: +82-31-910-7219, lys0326@paik.ac.kr

Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figures and Tables

Fig. 1

(A, B) Contrast-enhanced CT image shows a 3.6×4.3 cm sized enhancing mass (arrows) in porta hepatis. CT, computed tomography.

Fig. 2

Magnetic resonance cholangiopancreatography shows low signal intensity mass involving the common hepatic duct (white arrow).

Fig. 3

Endoscopic retrograde cholangiogram reveals biliary stricture of the common hepatic duct.

Fig. 4

Gross finding of the resected tumor shows a 4.7×4.5×3.5 cm sized protruding mass into the bile duct.

Fig. 5

Histopathologic findings. (A) Tumor cells shows trabecular arrangement. Cytoplasms are plump and deeply eosinophilic. Nuceli have round, smooth outline and dark chromatin (H&E, ×200). (B) Tumor cell cytoplasms are strongly stained with synaptophysin immunohistochemistry, which indicates neuroendocrine differentiation (synaptophysin, ×200).

Notes

^{Financial support} None.

^{Conflict of interest} None.

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ORCID iDs: Yoon Suk Lee
https://orcid.org/0000-0002-5835-9417
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