Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report

Joo-Yeon Kong; Hyo-Seok Kim; Seong-Chan Yeon; Jin-Kyu Park; Kyu-Shik Jeong; Il-Hwa Hong

doi:10.4142/jvs.2020.21.e1

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Kong, Kim, Yeon, Park, Jeong, and Hong: Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report

Case Report Pathology

J Vet Sci 2020;21(1):e1.

Published online: 4 January 2020

DOI: https://doi.org/10.4142/jvs.2020.21.e1

Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report

Joo-Yeon Kong¹, Hyo-Seok Kim¹, Seong-Chan Yeon², Jin-Kyu Park³, Kyu-Shik Jeong³, Il-Hwa Hong^1,^4,^*

¹Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea

²Department of Veterinary Clinical Sciences and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea

³Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea

⁴Institute of Animal Medicine, Gyeongsang National University, Jinju 52828, Korea

^*Corresponding author: Il-Hwa Hong Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University, 501 Jinju-daero, Jinju 52828, Korea. E-mail: ihhong@gnu.ac.kr

Received 19 July 2019 Revised 20 September 2019 Accepted 24 September 2019

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Tumor incidence in wild mammals is reportedly very low. Wild nutria, a large rodent, is known to carry many infectious diseases, but rarely exhibits neoplastic diseases. We necropsied a male wild nutria and found a large nodular mass in the left inguinal region, adjacent to the penis. Histopathologically, the mass was diagnosed as preputial gland adenoma. Spontaneous preputial gland adenomas are extremely rare in all animals. Moreover, reports of tumors in nutrias have been limited to adenocarcinomas of the lungs and uterus, as well as subcutaneous fibromas. Here, we describe preputial gland adenoma in a wild nutria.

Keywords: Adipophilin, nutria, preputial gland, sebaceous glands

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Fig. 1.

Necropsy of a male wild nutria. (A) The ventral aspect of the animal. The ventral skin has been peeled back, revealing a large muscle-covered mass (asterisk) lateral to the penis (arrow). (B) Cut surface of the mass. Yellowish exudates are observed.

Fig. 2.

Microscopic examination of the mass in a male wild nutria. (A) The mass is composed of reserved basal cells and secretory cells containing oily and waxy matter, which constitute a type of sebaceous gland. The gland has a long excretory duct with a wide lumen lined by hyperplastic squamous epithelium. (B, C) The tumor cells have a central round nucleus with one or (rarely) 2 large nucleoli. The cytoplasm contains small to large vacuoles. (D) Adipophilin is expressed in intracytoplasmic lipid vacuoles in sebaceous cells. Hematoxylin and eosin (A-C); immunohistochemistry of adipophilin (D) (all scale bar = 100 µm).

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