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Choi, Lee, and Yoo: Subcutaneous Panniculitis Like T Cell Lymphoma Initially Misdiagnosed as Behcet's Disease
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J Rheum Dis 2013;20(4):275-276.

Published online: 31 August 2013

DOI: https://doi.org/10.4078/jrd.2013.20.4.275

Subcutaneous Panniculitis Like T Cell Lymphoma Initially Misdiagnosed as Behcet's Disease

Yun Jung Choi1, Won Seok Lee2, Wan-Hee Yoo2

1Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, Korea

2Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea

Corresponding to : Wan-Hee Yoo, Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School, 20, Geonji-ro, Deokjin-gu, Jeonju 561-712, Korea. E-mail : ywhim@jbnu.ac.kr

Received 29 May 20139 August 2013       Accepted 9 August 2013

Copyright © 2013 The Korean College of Rheumatology

This is a Free Access article, which permits unrestricted non-commerical use, distribution, and reproduction in any medium, provided the original work is properly cited.

References

1. Gonzalez CL, Medeiros LJ, Braziel RM, Jaffe ES. T-cell lymphoma involving subcutaneous tissue. A clinicopathologic entity commonly associated with hemophagocytic syndrome. Am J Surg Pathol. 1991; 15:17–27.
2. Go RS, Wester SM. Immunophenotypic and molecular features, clinical outcomes, treatments, and prognostic factors associated with subcutaneous panniculitis-like T-cell lymphoma: a systematic analysis of 156 patients reported in the literature. Cancer. 2004; 101:1404–13.
3. Risulo M, Rubegni P, Sbano P, Sammassimo S, De Nisi MC, Leoncini L, et al. Subcutaneous panniculitis lymphoma: erythema nodosum-like. Clin Lymphoma Myeloma. 2006; 7:239–41.
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Figure 1.
A 24-year-old woman presented nodular subcutaneous skin lesions on the lower limbs (A). Infiltration of tumor cells confined to the subcutaneous tissue without involvement of the overlying dermis and epidermis was observed (×20, B). The tumor cells surrounded fat cells and were admixed with other inflammatory cells (×400, C). The tumor cells were positive for CD8 (D) and granzyme B (×400, E).
jrd-20-275f1.tif
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