Giant cell tumor is considered a benign tumor but it is also potentially malignant. It has a prediction to an end of a long bone in young adult. Despite of the voluminous literature on this rather common condition, the reports of the tumor involving the spine is surprisingly few. We experience a case of the tumor affecting the vertebral body of the lumbar spine. The Iesion was treated by radical curettage and anterior interbody fusion. At ten month follow-up, there was no recurrence. Further follow up is in order.