Abstract
Acute transverse myelitis is a rare clinical manifestation of Coxsackie virus
infection which cause acute and progressive debilitating illness associated with
loss of spinal cord function in the affected patients. A 62 year-old female
developed symptoms of rapidly progressive paraplegia with sensory loss. On
spinal MRI, T2 sagittal image showed increased signal intensity with cord
swelling at T11-L2 level and 8 folds or greater rise of Coxsackie virus B4
neutralizing antibody titers was observed in the CSF. There is only one previous
report of acute transverse myelitis caused by Coxsackie virus B4 infection to
our knowledge. The presence of specific viral antibody titers change in the CSF
and a corresponding spinal cord lesion are sufficient to suggest a causal
relationship between the virus and the illness. This article is a case report of
an unusual acute transverse myelitis caused by Coxsackie virus B4 infection.