| J Rhinol. 2015 May;22(1):28-33. Korean. Published online May 31, 2015. https://doi.org/10.18787/jr.2015.22.1.28 | |
| Copyright © 2015 The Korean Rhinologic Society | |
Seunghak Yu, MS,1
Jaewoon Wee, MD,2
Jeong-Whun Kim, MD, 2
and Sungroh Yoon, PhD1
| |
|
1Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea. | |
|
2Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. | |
| Corresponding author (
)
Corresponding author (
)
| |
| Received November 18, 2014; Revised January 25, 2015; Accepted February 05, 2015. | |
|
Abstract
| |
|
Background and Objectives
Sinus surgery has been reported to improve pulmonary function and decrease the use of asthma medications in patients with chronic rhinosinusitis and asthma. Most studies, however, have used a small number of patients and were conducted over a short period. To demonstrate a causal relationship between sinus surgery and asthma, a sufficient amount of patient data observed over a long period is required. To address the limitations of the existing approaches, we conducted a preliminary methodological study for large-scale data analysis using data from the National Health Insurance Service (NHIS) to suggest a basis for the effect of sinus surgery on asthma.
Materials and Methods
The data from NHIS consisted of unidentified medical histories of a sample cohort representing the whole nation over a period of nine years. We selected the following types of study samples: 1) patients with surgical codes for sinus surgery; 2) patients with disease codes for sinusitis; 3) patients with disease codes for asthma; and 4) patients with medication codes for asthma treatment.
Results
In this study, we applied a methodology for selection of subjects from big data to investigate the effect of sinus surgery on improving asthma in the future. We could include 152 subjects after the four-stage selection method from 1,025,340 patients.
Conclusion
We could establish a method to select patients with history of sinus surgery and asthma treatment from a big data. This methodology using big data may contribute to identify relationship between sinus surgery and asthma treatment in the future. |
|
Keywords: Big data; Health insurance service; Relation study; Sinus surgery; asthma |
|
|
Tables
|
|
|
|
|
References
|
| 1. | Raghupathi W, Raghupathi V. Big data analytics in healthcare: promise and potential. Health Inf Sci Syst 2014;2:3. 
|
| 2. | iHTT Report, Transforming Health Care Through Big Data Strategies for leveraging big data in the health care industry.
http://ihealthtran.com/wordpress/2013/03/iht%C2%B2-
|
| 3. | GINA Report, Global Strategy for Asthma Management and Prevention.
|
| 4. | Batra PS, Kern RC, Tripathi A, Conley DB, Ditto AM, Haines GK 3rd, et al. Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma. Laryngoscope 2003;113:1703–1706.
|
| 5. | Dunlop G, Scadding GK, Lund VJ. The effect of endoscopic sinus surgery on asthma: management of patients with chronic rhinosinusitis, nasal polyposis, and asthma. Am J Rhinol 1999;13:261–265.
|
| 6. | Garrel R, Gardiner Q, Khudjadze M, Demoly P, Vergnes C, Makeieff M, et al. Endoscopic surgical treatment of sinonasal polyposis-medium term outcomes (mean follow-up of 5 years). Rhinology 2003;41:91–96.
|
| 7. | Park AH, Lau J, Stankiewicz J, Chow J. The role of functional endoscopic sinus surgery in asthmatic patients. J Otolaryngol 1998;27:275–280.
|
| 8. | Uri N, Cohen-Kerem R, Barzilai G, Greenberg E, Doweck I, Weiler-Ravell D. Functional endoscopic sinus surgery in the treatment of massive polyposis in asthmatic patients. J Laryngol Otol 2002;116:185–189.
|
| 9. | Larsen K. The clinical relationship of nasal polyps to asthma. Allergy Asthma Proc 1996;17:243–249.
|
| 10. | Eriksson J, Bjerg A, Lötvall J, Wennergren G, Rönmark E, Torén K, et al. Rhinitis phenotypes correlate with different symptom presentation and risk factor patterns of asthma. Respir Med 2011;105:1611–1621.
|
| 11. | Lin DC, Chandra RK, Tan BK, Zirkle W, Conley D, Grammer LC, et al. Association between severity of asthma and degree of chronic rhinosinusitis. Am J Rhinol Allergy 2011;25:205–208.
|
| 12. | ten Brinke A, Grootendorst DC, Schmidt JT, De Bruïne FT, van Buchem MA, Sterk PJ, et al. Chronic sinusitis in severe asthma is related to sputum eosinophilia. J Allergy Clin Immunol 2002;109:621–626.
|
| 13. | Klossek JM, Neukirch F, Pribil C, Jankowski R, Serrano E, Chanal I, et al. Prevalence of nasal polyposis in France: a cross-sectional, case-control study. Allergy 2005;60:233–237.
|
| 14. | Downing E, Braman S, Settipane G. Bronchial reactivity in patients with nasal polyps before and after polypectomy. J Allergy Clin Immunol 1962;69:102.
|
| 15. | Matsuno O, Ono E, Takenaka R, Okubo T, Takatani K, Ueno T, et al. Asthma and sinusitis: association and implication. Int Arch Allergy Immunol 2008;147:52–58.
|
| 16. | Ragab A, Clement P, Vincken W. Objective assessment of lower airway involvement in chronic rhinosinusitis. Am J Rhinol 2004;18:15–21.
|
| 17. | Fokkens W, Lund V, Mullol J. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinol Suppl 2012;(23):3.
|
| 18. | Ehnhage A, Olsson P, Kolbeck KG, Skedinger M, Stjarne P. One year after endoscopic sinus surgery in polyposis: asthma, olfaction, and quality-of-life outcomes. Otolaryngol Head Neck Surg 2012;146:834–841.
|
| 19. | Proimos E, Papadakis CE, Chimona TS, Kiagiadaki D, Ferekidis E, Yiotakis J. The effect of functional endoscopic sinus surgery on patients with asthma and CRS with nasal polyps. Rhinology 2010;48:331–338.
|
| 20. | Ragab S, Scadding GK, Lund VJ, Saleh H. Treatment of chronic rhinosinusitis and its effects on asthma. Eur Respir J 2006;28:68–74.
|
| 21. | Senior BA, Kennedy DW, Tanabodee J, Kroger H, Hassab M, Lanza DC. Long-term impact of functional endoscopic sinus surgery on asthma. Otolaryngol Head Neck Surg 1999;121:66–68.
|
| 22. | Manning SC, Wasserman RL, Silver R, Phillips DL. Results of endoscopic sinus surgery in pediatric patients with chronic sinusitis and asthma. Arch Otolaryngol Head Neck Surg 1994;120:1142–1145.
|
Methodology for Big Data Analysis Using Data from National Health Insurance Service: Preliminary Methodologic Study and Review about the Relationship between Sinus Surgery and Asthma
