Journal List > Korean J Schizophr Res > v.15(1) > 1057774

Kim, Jae, Lee, Choi, and Park: The Effect of a 12-week Weight Management Program on the Quality of Life in Patients with Schizophrenia

Abstract

Objectives

This study was designed to examine the effect of a 12-week weight management program on the quality of life, self-esteem and psychotic symptoms of schizophrenia.

Methods

The subjects of the experiment consisted of psychiatric patients taking antipsychotics who were diagnosed with DSM-IV schizophrenia. The experimental group were patients with body mass index of 25 kg/m2 or above who participated in a 12-week weight management program, while the control group did not join the program. All the patients were admitted in closed psychiatry ward of a mental hospital. The program consisted of diet therapy, exercise, behavior modification and education. All the patients were checked on Brief Psychiatric Rating Scale (BPRS), Rosenberg Self-esteem Scale (RSES), Korean version of the SmithKlein Beecham Quality of Life (KvSBQOL), Korean version of 4th revision of Schizophrenia Quality of Life Scale (SQLS-R4K) and the weight.

Results

After the 12-week weight management program, RSES, KvSBQOL and SQLS-R4K were increased significantly in the experimental group (p<0.001), as opposed to the control group. While the experimental group showed a notable increase in body weight and body mass index (BMI), the change in the control group was insignificant. BPRS was decreased significantly (p<0.05).

Conclusion

12-week weight management program had a positive effect to decrease the weight and to increase the self-esteem and quality of life. This study provides evidence for the potential and beneficial effect of weight management program for schizophrenic patients. (Korean J Schizophr Res 2012;15:20–26)

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Fig. 1.
Change in body weight (A) and body mass index (BMI)(B) during 12-week weight management program. Body weight (A) and BMI was measured on the day 1 (Before) and the day 84 (After). **: p<0.001, vs. corresponding control, †: p<0.05, ††: p< 0.001, vs. corresponding the day 1.
kjsr-15-20f1.tif
Fig. 2.
Change in Brief Psychiatric Rating Scale (BPRS) during 12-week weight management program. BPRS was measured on the day 1 (Before) and the day 84 (After) by a psychiatrist. *: p< 0.05, vs. corresponding control, †: p<0.05, vs. corresponding the day 1.
kjsr-15-20f2.tif
Fig. 3.
Change in Rosenberg Self-esteem Scale (RSES)(A), Korean version of the SmithKlein Beecham Quality of Life (KvSBQOL) (B), Korean version of 4th revision of Schizophrenia Quality of Life Scale (SQLS-R4K)(C) during 12-week weight management program. RSES, KvSBQOL, SQLS-R4K were measured on the day 1 (Before) and the day 84 (After) by a psychiatrist. **: p<0.001, vs. corresponding control, ††: p<0.001, vs. corresponding the day 1.
kjsr-15-20f3.tif
Table 1.
Demographic characteristics of subjects
  EG (n=40)
CG (n=30)
χ2 or t p
Number (%) Number (%)
Gender, N     9.420 0.004*
 Male 26 (65) 16 (53.3)    
 Female 14 (35) 14 (46.7)    
Age, mean±SD 40.12±7.21 42.35±9.83 1.201 0.020*
Education, mean±SD 08.59±3.27 08.70±2.19 0.392 0.542*
Marital status, N     4.157 0.101*
 Single or divorced 18 (45) 15 (50)0.    
 Married 12 (55) 12 (40)0.    
 Widowers 0.0 (0.0) 02 (10)0.    
Risk factor of metabolic syndrome        
Hypertension     3.514 0.125*
systolic > 140 or diastolic > 90 23 (57.5) 15 (50)0.    
systolic ≤140 and diastolic<90 17 (42.5) 15 (50)0.    
Diabetes     2.001 0.064*
FBS≥126 26 (65) 17 (56.7)    
FBS<126 14 (35) 13 (43.3)    
Hyperlipidemia        
Total cholesterol     4.021 0.098*
 ≥220 mg/dL 24 (60) 19 (63.3)    
 <220 mg/dL 16 (40) 11 (36.7)    
LDL-cholesterol     1.523 0.071*
 ≥160 mg/dL 21 (52.5) 18 (60)0.    
 <160 mg/dL 19 (47.5) 12 (40)0.    
HDL-cholesterol     0.014 0.055*
 ≤35 mg/dL 21 (52.5) 20 (66.7)    
 > 35 mg/dL 19 (47.5) 10 (33.3)    

Statistics are tested by independent t-test for continuous variables and chi-square or Fisher's exact test statistics for categorical variables.

* p<0.05, †: p<Fisher's exact test. EG: Experimental group, CG: Control group

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