See the letter "Letter Regarding Article, "Electrocardiogram in a Patient with Takotsubo Syndrome and Cardiogenic Shock"" on page 179.
First of all, we would like to appreaciate your deep interest in our case report.1) Fortunately, we have a previous electrocardiogram (ECG) of the patient before the symptom onset (Fig. 1). And we did check the serial ECGs during the admission.
At initial admission, there were no prominent ST and voltage changes in precordial leads (Fig. 2). Follow-up ECG taken after 3 hours from the first ECG showed slight ST elevations of precordial leads (Fig. 3). The ECG findings seem to be consistent with low QRS voltage criteria of Takotsubo syndrome of the previous report.2) During hospital days 2 (Fig. 4) and 3 (Fig. 5), serial ECGs showed progressive worsening of previous low QRS voltages in all leads. On the 14th day of admission, QRS voltages in precordial limb leads became bigger with newly developed negative T-waves in leads V3–4 and flat T-wave in V5 (Fig. 6). And the ECG taken on hospital day 67 showed large QRS complexes in all precordial (> 10 mV) and limb (> 5 mV) leads except for a left ventricle lead (Fig. 7).
Unfortunately, we were not able to observe the evidence of myocardial edema during the acute phase because cardiac MRI examination was done at a later stage.
References
1. Yoo TK, Lee JY, Sung KC, Oh SS, Song YS, Lee SJ, Ko KJ. Stress-induced cardiomyopathy presenting as shock. J Cardiovasc Ultrasound. 2016; 24:79–83.
2. Madias JE. Transient attenuation of the amplitude of the QRS complexes in the diagnosis of Takotsubo syndrome. Eur Heart J Acute Cardiovasc Care. 2014; 3:28–36.