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Ham, Jang, and Han: Epidemiological Investigation of a Measles Outbreak in Seoul, 2013~2014
Communication

J Bacteriol Virol 2015;45(4):372-375.

Published online: 9 February 2015

DOI: https://doi.org/10.4167/jbv.2015.45.4.372

Epidemiological Investigation of a Measles Outbreak in Seoul, 2013~2014

Heejin Ham∗, Jungim Jang, Changho Han

Seoul Metropolitan Government Research Institute of Public Health and Environment, Virus Team, Gwacheon, Kyiunggido, Korea

∗Corresponding author: Heejin Ham. Seoul Metropolitan Government Research Institute of Public Health and Environment, 30 Janggunmaeul 3-gil, Gwacheon, Kyiunggido, 13818, Korea. Phone: +82-2-968-5094, Fax: +82-2-964-8174, e-mail: hhj3814@seoul.go.kr

∗∗ We are grateful to Respiratory Division of the Korean CDC related with this study. They had supported this study's sequencing data to us.

Received 24 June 201518 November 2015       Accepted 24 November 2015

Copyright © 2015 Journal of Bacteriology and Virology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Korea declared in 2006 that measles had been eliminated; however, a measles outbreak occurred in the southeastern area of Korea in 2011. Active surveillance of measles patients was conducted in Seoul 3 cases were detected in 2013 and 103 cases in 2014. Of 106 confirmed measles patients, 32 cases were within one university in Seongbukgu, and 23 were within three schools in Yongsangu. Students 14~29 years old comprised 78.3% (83/106) of the cases, and 75.5% (80/106) of the measles viruses were of genotype B3. One foreign traveler played an important role in the measles outbreak in Seoul. This measles outbreak in Seoul may provide useful data for future epidemiological studies of measles.

Keywords: Measles outbreak, Seoul, Genotype B3

REFERENCES

1). So JS, Go UY, Lee DH, Park KS, Lee JK. Epidemiological investigation of a measles outbreak in a preschool in Incheon, Korea, 2006. J Prev Med Public Health. 2008; 41:153–8.
crossref
2). Lee HD, Bae GR, Lee JY, Go UY, Yang BG, Yu MJ, et al. Survey on the epidemiological characteristics of measles incidence between 1980 and 1999 year in Korea. Kor J Infect Dis. 2002; 34:89–93.
3). Eom HS, Choi YJ. Status of measles after declaration on measles elimination in Korea, 2006–2011. Public health weekly report. KCDC. 2012; 1-6.
4). So JS, Go UY, Oh HK, Baek SJ, Lee JK. Assessment about the measles elimination from cases and outbreaks, 2002–2007, Assessment about the measles elimination. Kor J Pediatr. 2009; 52:68–74.
5). Shin GC, Na BK, Lee JY, Lee JS, Chung YS, Kang C. Deveploped of measles immunoglobulin M detecting enzyme-linked immunosorbent assay (IgM ELISA) using recombinant nucleoprotein of measles virus. J Bacteriol Virol. 2004; 34:223–30.
6). Jo HJ, Kang HJ. Genotyping analysis of measles outbreak in Korea in 2013, Public health weekly report. KCDC. 2014; 7:470–55.
7). Choi WS, Sniadack DH, Jee Y, Go UY, So JS, Cho H, et al. Outbreak of measles in the Republic of Korea, 2007: importance of nosocomial transmission. J Infect Dis. 2011; 204:483–90.
crossref
8). Eom HE, Kim JH. The investigation result of a small size measles outbreak in two difference provinces in Korea, 2013. Public health weekly report. KCDC. 2014; 7:278–80.

Figure 1.
Distribution of confirmed measles cases according to the location of transmission in Seoul, Republic of Korea during the 2013 outbreak.
jbv-45-372f1.tif
Figure 2.
Identified epidemiological linkage of measles transmission in Seoul, Republic of Korea, during the 2014 outbreak.
jbv-45-372f2.tif
Table 1.
Monthly distribution of confirmed measles cases in Seoul, Republic of Korea during the 2013~2014 outbreak.
Year Months 1 2 3 4 5 6 7 8 9 10 11 12 Total
2014 Sample No. 2 3 1 13 182 96 15 13 8 6 6 6 351
  Positive No.   2   2 74 23     1 1     103
2013 Sample No. Positive No.       3 2   3 3 1 2 4 1 2 1 4 23 3
Total Sample No. 2 3 1 16 190 96 18 16 10 10 8 10 374
  Positive No.   2   2 74 23   1 1 2 1   106
Table 2.
Distribution of confirmed measles cases according to age group in Seoul, Republic of Korea during the 2013~2014 outbreak
  Age group (2014) ()=No. positive
Year Gender Total 0~7 8~13. 14~16 . 17~19. 20~29. 30~39. 40~49. '50~ Unknown
2014 Male 210 (77) 41 (7) 11 (1) 12 (6) 80 (38) 50 (20) 8 (2) 4 (2) 1 (0) 3 (1)
Female 141 (26) 51 (2) 11 (1)     46 (19) 11 (1) 3 (1) 2 (0) 2 (2)
Total 351 (103) 92 (9) 22 (2) 12 (6) 80 (38) 96 (39) 19 (3) 7 (3) 3 (0) 5 (3)
2013 Male 7 (1) 5 (1)       2 (0)        
Female 11 (2) 8 (2) 2 (0)     1 (0)        
Unknown 5 (0)                 5 (0)
Total 23 (3) 13 (3) 2 (0)     3 (0)       5 (0)
Total Male 217 (78) 46 (8) 11 (1) 12 (6) 80 (38) 52 (20) 8 (2) 4 (2) 1 (0) 3 (1)
Female 152 (28) 59 (4) 13 (1)     47 (19) 11 (1) 3 (1) 2 (0) 2 (2)
Unknown 5 (0)                 5 (0)
Total 374 (106) 105 (12) 24 (2) 12 (6) 80 (38) 99 (39) 19 (3) 7 (3) 3 (0) 10 (3)
Table 3.
Serotype distribution of confirmed measles cases in Seoul, Republic of Korea during the 2013– 2014 outbreak
Serotypes of measles virus Confirmed viruses
Serotype A 1
Serotype B3 80
Serotype D9 1
Unknown other serotypes 24
Total 106
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