Journal List > Tuberc Respir Dis > v.71(6) > 1001687

Lee, Lee, Choi, and Lee: The Application of Impulse Oscillometry (IOS) in the Workers Who had been Exposed to Inorganic Dust Induced Early Airway Obstruction

Abstract

Background

We tried to examine the small airway diseases which can be found early, in workers exposed to inorganic dusts. This is measured in normal breath by using the impulse oscillometry (IOS).

Methods

The Pulmonary function test (forced vital capacit [FVC], forced expiratory volume in one second [FEV1], forced expiratory flow between 25% and 75% of vital capacity [FEF25-75]), IOS resistance (Rrs at 5, 10, 15, 20, 25, 35 Hz) and reactance (Xrs at 5, 10, 15, 20, 25, 35 Hz) were measured for 454 workers. The subjects were classified into 173 workers of normal (38.1%) and 281 patients with pneumoconiosis (61.9%).

Results

There were significant differences between normal and patients with FVC (3.82±0.61 vs. 3.53±0.56 L), FEV1 (2.67±0.63 vs. 2.35±0.48 L), and FEF25-75 (1.88±0.95 vs. 1.47±0.80 L/sec) between groups (p<0.05). And as for IOS, there was no significant difference in resistance (Rrs) (p>0.05), and there were significant differences between normal and patients with reactance (Xrs) 15 Hz (0.003±0.05 vs. -0.006±0.04 kPa/L/s), 20 Hz (0.043±0.05 vs. 0.031±0.04 kPa/L/s), and 35 Hz (0.141±0.05 vs. 0.131±0.05 kPa/L/s) between groups (p<0.05).

Conclusion

We could find out that 15 Hz, 20 Hz, and 35 Hz values of reactance were significantly influenced by pneumoconiosis. When usefulness and reproducibility to carry out the IOS are considered, it is thought that in future work will be required to draw the reference values for normal Korean persons.

Figures and Tables

Figure 1
Comparison of resistance parameters between the control and Pneumoconiosis group (p>0.05). Rrs: resistance.
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Figure 2
Comparison of reactance parameters between the control and Pneumoconiosis group. Xrs: reactance.
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Table 1
Characteristics of the subjects
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*Pearson Chi-square test.

Table 2
Comparison of spirometry parameters between the control and Pneumoconiosis group
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Data are expressed as mean±SD.

*Student t-test.

FVC: forced vital capacity; FVC%: percent of FVC; FEV1: forced expiratory volume in one second; FEV1%: percent of FEV1; FEV1/FVC%: percent of FEV1/FVC; FEF25-75: forced expiratory flow between 25% and 75%; FEF25-75%: percent of FEF25-75; SD: standard deviation.

Table 3
Comparison of airway resistance parameters between the control and Pneumoconiosis group
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Data are expressed as mean±SD. Unit is kPa/L/s.

*Student t-test.

SD: standard deviation.

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