Changes in Anterior Chamber Depth and Refraction after Accommodative Intraocular Lens Implantation

Jae Hui Kim; Chun-Sung Park; Eui-Sang Chung; Tae-Young Chung

doi:10.3341/jkos.2007.48.11.1479

Journal List > J Korean Ophthalmol Soc > v.48(11) > 1007959

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Kim, Park, Chung, and Chung: Changes in Anterior Chamber Depth and Refraction after Accommodative Intraocular Lens Implantation

Original Article

J Korean Ophthalmol Soc 2007;48(11):1479-1486.

Published online: 28 August 2007

DOI: https://doi.org/10.3341/jkos.2007.48.11.1479

Changes in Anterior Chamber Depth and Refraction after Accommodative Intraocular Lens Implantation

Jae Hui Kim, M.D., Chun-Sung Park, M.D., Eui-Sang Chung, M.D., Tae-Young Chung, M.D.

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Address reprint requests to Tae-Young Chung, M.D., Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine #50 Ilwon-dong, Gangnam-gu, Seoul 130-710, Korea, Tel: 82-2-3410-3563, Fax: 82-3410-0074, E-mail: tychung@smc.samsung.co.kr

Received 7 March 2007 Accepted 24 July 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the change in anterior chamber depth and refraction after AT-45 implantation Methods: Twenty-two eyes from 22 patients were enrolled in this prospective study. After phacoemulsification, AT-45 (11 eyes) and SA60AT (11 eyes) were implanted. Clinical data included anterior chamber depth and refractive error at 1 week, 1 month, 2 months and 6 months postoperatively. The correlation between anterior chamber depth change and spherical equivalent change was also evaluated.

Results

In the AT-45 implanted group, the mean anterior chamber depth was 4.56±0.59 mm at 1 week postoperative, 4.70±0.69 mm at 1 month postoperative, 4.78±0.71 mm at 2 months postoperative and 4.76± 0.69 mm at 6 months postoperative. The mean spherical equivalent was −0.53±0.48D, −0.37±0.42D, −0.27± 0.47D, and −0.33±0.44D respectively. When analyzed using the Mann-Whitney U test, p-values of anterior chamber depth differences between the 2 groups were P=0.52 at 1 week to 1 month, P=0.32 at 1 month to 2 months, P=0.89 at 2 months to 6 months, and P=0.02 at 1 week to 6 months, showing a deeper anterior chamber in the AT-45 implanted group. P-values (Mann-Whitney U test) of spherical equivalent differences between the 2 groups were P=0.33, P=0.56, P=0.94, and P=0.19, respectively, showing more hyperopic change in the AT-45 implanted group. The correlation between anterior chamber depth change and spherical equivalent change in the AT-45 implanted group at 1 week to 6 months was not statistically significant (Spearman correlation analysis, P=0.223).

Conclusions

Anterior chamber depth deepening and associated hyperopic refractive change were observed after AT-45 implantation, especially at 1 month after the surgery.

Keywords: Accommodative IOL, Anterior chamber depth, AT-45, Crystalens, Refraction

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Figure 1.

Changes in mean anterior chamber depth (ACD) after AT-45 (n=11) and SA60AT (n=11) implantation, according to the follow-up period.

Figure 2.

Mean anterior chamber depth (ACD) difference in AT-45 group (n=11) and SA60AT group (n=11), according to the follow-up period. Positive value represents deepening of the anterior chamber, whereas negative value represents shallowing of the anterior chamber (^* : Mann-Whitney U test, W: week, M: month).

Figure 3.

Mean spherical equivalent (SE) change after AT-45 (n=11) and SA60AT (n=11) implantation, according to the follow-up period.

Figure 4.

Mean spherical equivalent (SE) difference in AT-45 group (n=11) and SA60AT group (n=11), according to the follow-up period. Positive value represents hyperopic change, whereas negative value represents myopic change in spherical equivalent (^* : Mann-Whitney U test, W: week, M: month).

Figure 5.

Anterior chamber depth (ACD) and spherical equivalent (SE) change in AT-45 implanted group. Correlation between ACD change and SE change between 1 week and 6 months was not statistically significant (Spearman correlation analysis, P=0.223).

Table 1.

Patients’ demographics

	AT-45 group	SA60AT group	P-value
Male / female (number of eyes)	7 / 4	6 / 5	1.000^†
Age (years)	54.55± 14.58^*	61.45±6.54^*	0.133^‡
Axial length (mm)	23.67±0.43^*	23.26±0.82^*	0.088^‡
Implanted IOL (diopter)	21.18± 1.87^*	20.7 5± 1.95^*	0.468^‡
Predicted postoperative refraction (diopter)	-0.62±0.08^*	-0.60±0.18^*	0.478^‡

^* : Mean±Standard deviation;

^† : Fisher's Exact Test;

^‡ : Mann-Whitney U test.

Table 2.

Mean anterior chamber depth (ACD) and spherical equivalent (SE) difference in AT-45 group (n=11) and SA60AT group (n=11), according to the follow-up (F/U) period. Positive value represents deepening of the anterior chamber, whereas negative value represents shallowing of the anterior chamber in ACD change. Positive value represents hyperopic change, whereas negative value represents myopic change in SE in SE change

	F/U period	AT-45	SA60AT	P-value
Mean±SD (mm)
ACD	1W∼1M	0.14±0.25	0.03±0.18	0.52^*
	1M∼2M	0.07±0.20	-0.01±0.15	0.32^*
	2M∼6M	-0.02±0.24	-0.04±0.18	0.89^*
	1W∼6M	0.19±0.28	-0.02±0.25	0.02^*
Mean±SD (diopter)
SE	1W∼1M	0.15±0.37	0.05±0.20	0.33^*
	1M∼2M	0.10±0.30	0.03±0.25	0.56^*
	2M∼6M	-0.06±0.32	-0.08±0.18	0.94^*
	1W∼6M	0.20±0.50	0.01±0.31	0.19^*

^* : Mann-Whitney U test; SD: standard deviation; W: week; M: month.

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